Exercise program to help with bladder pain syndrome
Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome
This study is testing whether a guided exercise program can help people with bladder pain syndrome feel better and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Female |
| Sponsor | Wake Forest University Health Sciences Academic / other |
| Drugs / interventions | radiation, cyclophosphamide |
| Locations | 1 site (Winston-Salem, North Carolina) |
| Trial ID | NCT05699551 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of a supervised exercise program led by a trained exercise physiologist to alleviate symptoms and improve quality of life for patients suffering from interstitial cystitis/bladder pain syndrome. The research aims to assess not only the physical benefits of exercise on bladder-related symptoms but also its impact on depressive symptoms, which often accompany this condition. Additionally, the study will evaluate urinary markers of inflammation before and after the exercise regimen. This approach seeks to provide a non-invasive, cost-effective therapeutic strategy for managing a challenging condition.
Who should consider this trial
Good fit: Ideal candidates are adult females aged 18 to 80 with a clinical diagnosis of interstitial cystitis/bladder pain syndrome.
Not a fit: Patients who are not fully ambulatory or unable to tolerate moderate aerobic exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new, effective treatment option for patients suffering from interstitial cystitis/bladder pain syndrome.
How similar studies have performed: While the approach of using exercise as a therapeutic strategy for this condition is relatively novel, similar studies in other chronic pain conditions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult females (\>18 years and \<80 years) with a previously established clinical diagnosis of Interstitial cystitis/bladder pain syndrome (IC/BPS) will be eligible to participate * Must speak English * The clinical diagnosis of IC/BPS will be based on the recently published American Urological Association Guidelines definition: "An unpleasant sensation (pain, pressure, or discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms for more than six weeks duration, in the absence of infection or other identifiable causes" * The diagnosis will be confirmed by a urologist who specializes in the treatment of patients with IC/BPS Exclusion Criteria: * Study participants must be fully ambulatory without the use of a cane, walker, or wheelchair * Study participants must be able to tolerate moderate aerobic exercise. It will also be required that a physician clear any subjects entering the exercise program who have signs and symptoms suggestive of cardiovascular, cerebrovascular, metabolic, or renal disease and have been active 3 days per week for 30 minutes each day * Any history of bladder cancer, uterine cancer, ovarian cancer, vaginal cancer, the current placement of a catheter, urethral diverticulum, spinal cord injury, stroke, Parkinson's disease, multiple sclerosis, spina bifida, cyclophosphamide treatment, radiation cystitis, bladder tuberculosis, or are experiencing an active genital herpes episode * Pregnant women are not eligible for this study
Where this trial is running
Winston-Salem, North Carolina
- Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Stephen J Walker, PhD — Wake Forest University Health Sciences
- Study coordinator: Stephen J Walker, PhD
- Email: swalker@wakehealth.edu
- Phone: 3367493574
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.