Exercise program to help with bladder pain syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of a supervised exercise program led by a trained exercise physiologist to alleviate symptoms and improve quality of life for patients suffering from interstitial cystitis/bladder pain syndrome. The research aims to assess not only the physical benefits of exercise on bladder-related symptoms but also its impact on depressive symptoms, which often accompany this condition. Additionally, the study will evaluate urinary markers of inflammation before and after the exercise regimen. This approach seeks to provide a non-invasive, cost-effective therapeutic strategy for managing a challenging condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult females (\>18 years and \<80 years) with a previously established clinical diagnosis of Interstitial cystitis/bladder pain syndrome (IC/BPS) will be eligible to participate
* Must speak English
* The clinical diagnosis of IC/BPS will be based on the recently published American Urological Association Guidelines definition: "An unpleasant sensation (pain, pressure, or discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms for more than six weeks duration, in the absence of infection or other identifiable causes"
* The diagnosis will be confirmed by a urologist who specializes in the treatment of patients with IC/BPS

Exclusion Criteria:

* Study participants must be fully ambulatory without the use of a cane, walker, or wheelchair
* Study participants must be able to tolerate moderate aerobic exercise. It will also be required that a physician clear any subjects entering the exercise program who have signs and symptoms suggestive of cardiovascular, cerebrovascular, metabolic, or renal disease and have been active 3 days per week for 30 minutes each day
* Any history of bladder cancer, uterine cancer, ovarian cancer, vaginal cancer, the current placement of a catheter, urethral diverticulum, spinal cord injury, stroke, Parkinson's disease, multiple sclerosis, spina bifida, cyclophosphamide treatment, radiation cystitis, bladder tuberculosis, or are experiencing an active genital herpes episode
* Pregnant women are not eligible for this study

Where it's running

• Wake Forest University Health Sciences
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Stephen J Walker, PhD — Wake Forest University Health Sciences
• Study coordinator: Stephen J Walker, PhD
• Email: swalker@wakehealth.edu
• Phone: 3367493574

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Treatment of bladder pain using VNX001

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• Acupuncture for treating bladder pain syndrome in women

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• Assessing pain types in treating bladder pain syndrome

  This study is trying to see how different types of bladder pain affect how well people with bladder pain syndrome respond to pelvic floor physical therapy and cognitive-behavioral therapy.

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• Evaluating VNX001 for bladder pain relief in patients with interstitial cystitis

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  Recruiting at 11 sites Phase 2 Vaneltix Pharma, Inc. · Escondido, California and 13 other locations · NCT05737121

• PEMF therapy for women with bladder pain syndrome

  This study is testing if a new non-invasive treatment using pulsed electromagnetic fields can help women with bladder pain syndrome feel less pain and improve their urinary symptoms.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT05149573

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.