Exercise program for patients with Post-Concussion Syndrome
Rehabilitation of Adult Patients With Post Concussion Syndrome
This study tests whether a special exercise program can help people with Post-Concussion Syndrome feel better and improve their physical abilities after a mild brain injury.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Rigshospitalet, Denmark Academic / other |
| Locations | 1 site (Copenhagen, Region of Greater Copenhagen) |
| Trial ID | NCT05785000 on ClinicalTrials.gov |
What this trial studies
This project evaluates the effects of a tailored exercise program on patients suffering from Post-Concussion Syndrome (PCS) following mild traumatic brain injury. It consists of four parts: understanding patient experiences through interviews, assessing the impact of a 12-week aerobic exercise program on physical capacity, measuring neurobiological changes via MRI, and conducting a comprehensive evaluation involving both patients and researchers. The study aims to enhance physical capacity and provide insights into the neurobiological underpinnings of PCS.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with Post-Concussion Syndrome who have experienced symptoms for at least four weeks following a mild traumatic brain injury.
Not a fit: Patients with other serious brain diseases or severe cardiovascular conditions that prevent participation in physical activity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and recovery strategies for patients with long-lasting symptoms after concussion.
How similar studies have performed: Other studies have shown promise in using exercise as a therapeutic intervention for concussion-related symptoms, suggesting a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Post concussion syndrome (PCS) diagnose according to WHO ICD-10 classification and documented by written statement from physician veritying a mild traumatic brain injury * Longer lasting symptoms for at least 4 weeks after initial trauma * If allocated to add-on exercise protocol participant must feel able to prioritize the intervention structure * Communication language must be Danish Exclusion Criteria: * Other diseases blurring the diagnose PCS * Other serious brain diseases * Severe cardiovascular diseases precluding physical activity according to protocol
Where this trial is running
Copenhagen, Region of Greater Copenhagen
- University College Copenhagen — Copenhagen, Region of Greater Copenhagen, Denmark (Recruiting)
Study contacts
- Principal investigator: Henrik BW Larsson, Professor — Faculty of Health and Medical Science, University of Copenhagen, Denmark
- Study coordinator: Henrik BW Larsson, Professor
- Email: henrik.bo.wiberg.larsson@regionh.dk
- Phone: (+45) 24824294
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.