Clinical trial Recruiting at 1 site Interventional Ages 20 to 72

Using 7 Tesla MRI to Diagnose Post-Concussion Syndrome in Mild Traumatic Brain Injury Patients

Official title: Interest of the 7 Tesla MRI in the Diagnosis of Post-concussion Syndromes Among Patients With Mild Traumatic Brain Injury

Run by Poitiers University Hospital · NCT04982562 · Data updated 2026-11-12

This study is testing if a special type of MRI can help doctors find hidden brain injuries in people with mild head trauma who are experiencing ongoing concussion symptoms.

Quick facts

Study typeInterventional
Ages20 Years to 72 Years
SexAll
Enrollment100 (estimated)
SponsorPoitiers University Hospital
Academic / other
Locations1 site (Poitiers)
StatusRecruiting
StartedJune 26, 2021
Main results expectedJune 13, 2026
Study endsJune 13, 2027
Registry record updatedMay 22, 2026
Trial IDNCT04982562 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 18 and older who have sustained a mild traumatic brain injury and are experiencing post-concussion symptoms.

Probably not a fit

Patients with psychiatric disorders, severe obesity, or contraindications for MRI will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of 7 Tesla MRI in detecting diffuse axonal lesions in patients who have experienced mild traumatic brain injury and are presenting with post-concussion syndrome. Conducted at Poitiers University Hospital, the study will involve patients who are admitted for mild head trauma and will assess their condition seven days post-injury. The goal is to determine if this advanced imaging technique can improve diagnostic accuracy compared to standard methods. By identifying these lesions, the study seeks to better understand the relationship between brain injuries and persistent post-concussion symptoms.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic capabilities for post-concussion syndrome, potentially reducing long-term symptoms and associated healthcare costs.

How similar studies have gone: While there is emerging literature on the use of advanced MRI techniques for brain injury diagnosis, this specific approach using 7 Tesla MRI is relatively novel and has not been extensively tested in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mild traumatic brain injury with glascow included between 13 and 15, with indication of scan
* possibilty of performing an MRI at 7 days
* Patient able to get to MRI at Day 7
* Free consentement to the study
* Any measure of guardianship or curatorship , any link of subordination

Exclusion Criteria:

* Patient does not hospitalized about head trauma
* Inhability to move out for run the seven day MRI
* Contraindication for MRI
* Patient having already consulted the emergency for head trauma requiring imaging
* Patients with psychiatric troubles : bipolarity, panic trouble, depressive trouble, schizophrenia
* Patient already enrolled in the study
* History of brain, tumor or neurosurgery
* Untreated or poorly treated chronic vertigo
* Untreated or poorly treated chronic migraines
* Claustrophobia
* BMI \> 40
* Refusal of consent to take part of the study
* No social welfare or inhability to benefit of it by a third party
* Patients with enhanced protection : minor aged under 18 ; person with freedom restriction by justice decision or administrative ; homeliving in health or social establishment ; adult in legal protection
* Pregnant and nursing women

Where it's running

  • CHU Poitiers
    Poitiers, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.