Exercise program for improving breathing in obstructive sleep apnea
Combining Sonography to Explore the Therapeutic Effect and Mechanism of a Comprehensive Respiratory Training Exercise Program on Cardiorespiratory Endurance and Airway Muscle Function in Obstructive Sleep Apnea
This study is testing whether a special exercise program can help people with newly diagnosed obstructive sleep apnea breathe better and improve their sleep quality.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 20 Years to 65 Years |
| Sex | All |
| Sponsor | National Cheng-Kung University Hospital Academic / other |
| Locations | 1 site (Tainan, Taiwan) |
| Trial ID | NCT05739617 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the feasibility and effectiveness of a comprehensive respiratory training exercise program for patients with obstructive sleep apnea (OSA). Participants aged 20-65, newly diagnosed with OSA, will be randomly assigned to either an intervention group, which will undergo a 3-month exercise program, or a control group receiving sleep hygiene education. Various assessments, including polysomnography and cardiopulmonary exercise testing, will be conducted before and after the intervention to measure changes in cardiorespiratory endurance, airway muscle function, and sleep quality. The study seeks to understand the therapeutic effects and mechanisms of the exercise program on OSA severity.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20-65 with a newly diagnosed obstructive sleep apnea and a body mass index between 18-30 kg/m².
Not a fit: Patients with central or mixed sleep apnea, severe cardiovascular disease, or other specified exclusions may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could improve cardiorespiratory endurance and reduce the risk of cardiovascular diseases in patients with obstructive sleep apnea.
How similar studies have performed: While there is limited data on this specific exercise approach, similar interventions have shown promise in improving outcomes for patients with obstructive sleep apnea.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed with OSA (AHI≥ 5 events per hour) * Age between 20 to 65 years old * BMI of 18-30 kg.m-2 Exclusion Criteria: Diagnosed with any of the following diseases below: * Central or mixed types of sleep apnea * Neuromuscular disease * Severe cardiovascular disease * Active psychiatric disease * Head or neck disease or cancer * Structural abnormalities over the upper respiratory airway * Performed any operation or treatment over the neck before * Pregnancy
Where this trial is running
Tainan, Taiwan
- National Cheng Kung University Hospital — Tainan, Taiwan, Taiwan (Recruiting)
Study contacts
- Principal investigator: Ching-Hsia Hung, PhD — National Cheng Kung University
- Study coordinator: Jun-Hui Ong, MS
- Email: junhui.ong611@gmail.com
- Phone: +886-9-37839992
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.