Training to strengthen breathing muscles in people with obstructive sleep apnea
Effect of Inspiratory Muscle Training on Daytime Sleepiness in Obstructive Sleep Apnea Syndrome : Prospective Randomized Controlled Trial
This study is testing if a special breathing exercise program can help adults with obstructive sleep apnea feel less sleepy during the day and improve their breathing at night while using CPAP.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 58 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Régional d'Orléans Academic / other |
| Locations | 1 site (Orléans) |
| Trial ID | NCT06117579 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of inspiratory muscle training (IMT) on patients with obstructive sleep apnea (OSA), a condition characterized by interruptions in breathing during sleep. The research aims to assess whether IMT can improve the apnea-hypopnea index and reduce daytime sleepiness, thereby enhancing the quality of life for affected individuals. Participants will undergo a structured training program designed to strengthen the diaphragm and other respiratory muscles, potentially serving as an adjunct therapy to the standard continuous positive airway pressure (CPAP) treatment. The study will include adults over 18 years of age diagnosed with OSA who require CPAP.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with obstructive sleep apnea and an apnea-hypopnea index of 5 or greater who require CPAP.
Not a fit: Patients with sleep apnea of neurological or mixed origin, those who cannot use CPAP, or individuals with cognitive disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide an effective complementary treatment for patients with obstructive sleep apnea, improving their overall quality of life.
How similar studies have performed: While inspiratory muscle training has been explored in limited studies, the efficacy of this specific approach in treating obstructive sleep apnea remains novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients over 18 years of age with * OSA with an Apnea Hypopnea Index ≥ 5 requiring CPAP Exclusion Criteria: * Sleep apnea of neurological or mixed origin, * Contraindication to or refusal of CPAP, * Cognitive disorders, * protected persons (under guardianship or curatorship), * persons under court protection, * persons not affiliated to a social security scheme * pregnant or breast-feeding women.
Where this trial is running
Orléans
- Chu Orleans — Orléans, France (Recruiting)
Study contacts
- Principal investigator: Marie DEVAUX, Dr — CHU d'Orléans
- Study coordinator: Aurelie DESPUJOLS, Msc
- Email: aurelie.despujols@chu-orleans.fr
- Phone: +332 38 74 40 71
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.