Melatonin's effects on sleep and blood pressure in patients with obstructive sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of melatonin in treating insomnia and restoring normal blood pressure patterns in adults diagnosed with obstructive sleep apnea (OSA). Participants will take melatonin or their usual treatment daily for one month while attending multiple clinic visits. They will monitor their symptoms and activities, undergo blood pressure assessments, and participate in sleep studies to evaluate the impact of melatonin on their sleep quality and blood pressure regulation. The study aims to determine if melatonin can improve sleep maintenance and restore the dipping blood pressure pattern typically seen during sleep.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Polisomnographic diagnosis of Obstructive Sleep Apnea
* Non-dipping blood pressure on Ambulatory blood pressure monitoring (ABPM):

Exclusion Criteria:

* Use of sleep or psychiatric medication
* Use of Positive Airway Pressure (CPAP or Bipap)
* Neurologic or psychiatric disorder

Where it's running

• National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ)
  Mexico City, Mexico Recruiting

Study contacts

• Principal investigator: Matilde Valencia-Flores, PhD — National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ)
• Study coordinator: Matilde Valencia-Flores, PhD
• Email: matilde.valenciaf@incmnsz.mx
• Phone: (+52 55) 54870900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using smartwatches to predict obstructive sleep apnea

  This study is testing whether smartwatches can help find signs of obstructive sleep apnea by tracking health data while you sleep.

  Recruiting Seoul National University Hospital · Seoul · NCT06792188

• Evaluating the effects of hypoglossal nerve stimulation on metabolism in sleep apnea patients

  This study is testing if a therapy that stimulates a nerve in the tongue can help people with sleep apnea improve their metabolism and reduce health risks.

  Recruiting Columbia University · New York, New York · NCT06720545

• Assessing OSA risk in dental patients undergoing general anesthesia

  This study is trying to see how many dental patients who will be put under general anesthesia might have obstructive sleep apnea and if it affects their recovery.

  Recruiting at 2 sites Kırıkkale University · Kayseri and 1 other locations · NCT06430957

• Effects of GLP-1 Agonists After Bariatric Surgery

  This study is testing whether continuing or stopping a specific diabetes medication after weight loss surgery helps improve health for people who have had gastric bypass or sleeve gastrectomy.

  Recruiting Phase 4 University of Missouri-Columbia · Columbia, Missouri · NCT06132477

• Training to strengthen breathing muscles in people with obstructive sleep apnea

  This study is testing if a special breathing exercise program can help adults with obstructive sleep apnea feel less sleepy during the day and improve their breathing at night while using CPAP.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT06117579

• Oropharyngeal exercises for obstructive sleep apnea patients using a mandibular advancement device

  This study is testing if special exercises for the throat and tongue can help adults with obstructive sleep apnea who are already using a mouth device to sleep better.

  Recruiting National Cheng-Kung University Hospital · Tainan · NCT06103630

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.