Exercise program for children with cancer to improve insulin sensitivity
Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity
This study is testing if an exercise program can help improve insulin sensitivity and overall health in children with cancer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 5 Years to 18 Years |
| Sex | All |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Trial ID | NCT05383092 on ClinicalTrials.gov |
What this trial studies
This study evaluates how intense physical activity affects insulin sensitivity and other metabolic, motor, and nutritional factors in children diagnosed with cancer. Over a period of six months, participants will engage in either intense physical activities or stretching programs, with evaluations conducted at multiple intervals. The sessions will be tailored to each child's needs and abilities, taking place in the hospital or via videoconference. The goal is to determine if exercise can enhance health outcomes for these children.
Who should consider this trial
Good fit: Ideal candidates are children aged 5 to 18 years who are newly diagnosed with solid or hematological cancers and have a life expectancy of more than six months.
Not a fit: Patients with physical or psychological limitations that prevent participation in an exercise program, or those with certain pre-existing health conditions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly improve metabolic health and overall well-being in children undergoing cancer treatment.
How similar studies have performed: Previous studies have shown positive outcomes with exercise interventions in pediatric cancer patients, suggesting this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age between 5 and 18 years old; * have a solid cancer or hematological disease; * be treated for the first time in pediatric oncology and hematology department; * have an estimated life expectancy at diagnosis of more than 6 months. Exclusion Criteria: * present a physical and/or psychological impossibility to follow an adapted physical activity program; * have a pre-existing heart disease that is not suitable for adapted physical activities; * have a known type 1 diabetes * have an obesity defined by a body mass index greater than or equal to the International Obesity Task Force 25 threshold
Where this trial is running
Toulouse
- PASQUET Marlène — Toulouse, France (Recruiting)
Study contacts
- Principal investigator: Marlène PASQUET, MD, PhD — University Hospital, Toulouse
- Study coordinator: Marlène PASQUET, MD, PhD
- Email: pasquet.m@chu-toulouse.fr
- Phone: 05 34 55 86 08
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.