Exercise program for breast cancer patients
Official title: Breast Cancer Exercise Intervention Study (BREXINT)
Run by National Cancer Centre, Singapore · NCT05957068 · Data updated 2026-11-12
This study tests whether a 24-week exercise program can improve fitness, strength, and quality of life for breast cancer patients who have finished their treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 99 Years |
| Sex | Women only |
| Enrollment | 2156 (estimated) |
| Sponsor | National Cancer Centre, Singapore Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 3 sites (Singapore and 2 other locations) |
| Status | Recruiting |
| Started | July 1, 2023 |
| Main results expected | May 31, 2028 |
| Study ends | May 31, 2033 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT05957068 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are females aged 21 and older with stage 1, 2, or 3 breast cancer who have recently undergone curative surgery and completed any necessary adjuvant treatments.
✕Probably not a fit
Patients with significant cardiovascular, respiratory, or musculoskeletal issues that prevent moderate physical activity may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial involves a 24-week exercise program designed for patients with early-stage and locally advanced breast cancer who have undergone curative surgery and completed chemotherapy or radiotherapy. The program includes aerobic exercise and muscle strength training, with the first nine sessions supervised in person by physiotherapists, followed by remote monitoring or supervision at local gyms. The study aims to assess the impact of this exercise intervention on cardiorespiratory fitness, muscle strength, and quality of life among participants. Blood samples and questionnaires will be collected periodically to evaluate health outcomes.
Why it matters
Potential benefit: If successful, this program could enhance physical fitness and quality of life for breast cancer survivors.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions for cancer patients, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with histologically or cytologically proven stage 1, 2, or 3 breast cancer * Patients who have undergone curative breast surgery * Patients who have received (neo)adjuvant chemotherapy (if given) and/or radiotherapy (if given) * Females aged 21 years and older * ≤ 8 weeks from breast surgery, or the last adjuvant chemotherapy or radiotherapy session, whichever is latest. Exclusion Criteria: * Cardiovascular, respiratory, musculoskeletal problems that preclude moderate physical activity. * Major medical problems that are deemed by the investigator to be unsuitable for enrollment.
Where it's running
-
National University Hospital
Singapore, Singapore Recruiting -
National Cancer Centre
Singapore, Singapore Recruiting -
Singapore General Hospital
Singapore, Singapore Recruiting
Study contacts
- Principal investigator: Dr Elaine LIM, MD, PhD — National Cancer Centre, Singapore
- Study coordinator: Dr Elaine LIM, MD, PhD
- Email: elaine.lim.hsuen@singhealth.com.sg
- Phone: +65 64368000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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-
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Culmerciclib with endocrine therapy before surgery for early HER2-negative hormone receptor-positive breast cancer
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.