Exercise plus noninvasive brain stimulation for breast cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a feasibility study to see if a 4-week program that pairs aerobic exercise with transcranial alternating current stimulation is workable for breast cancer survivors with self-reported cognitive impairment. The trial will measure how many participants stay in the study, how well they adhere to the regimen, satisfaction, and safety. It will also look at changes in attention, executive function, working memory, perceived cognitive function, and physical function before, after, and four weeks post-intervention, comparing Ex+tACS to a control group receiving exercise with a sham tACS. Results will inform whether a larger, more definitive study is warranted.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Breast cancer survivors (≥18 years) will be eligible to participate if the following inclusion criteria is met:
* Diagnosed non-metastatic breast cancer (stages 0-3)
* Completed primary breast cancer treatment (surgery, chemotherapy, radiation) for at least 3 months
* Self-reported cognitive impairment after cancer treatment

Exclusion Criteria:

* Current participation in aerobic exercise for ≥60 min/wk
* Contraindication or impairment that precludes the potential participant from exercise as defined by the American College of Sports Medicine
* The presence of serious medical illnesses, metal implants, previous brain trauma, epilepsy or history of seizures, previous surgery to the head or spinal cord, or skin problems at the forehead area where the tACS electrodes will be applied
* Uncontrolled cardiovascular disease
* Functional impairments or physical condition that would make exercise unsafe
* Metastatic cancer or diagnosis of a different cancer (excluding melanoma) within the past 5 years
* Contraindication to exercise a defined by the American College of Sports Medicine

Where it's running

• Florida Atlantic University
  Boca Raton, Florida, United States Recruiting

Study contacts

• Study coordinator: Ashley L Artese, PhD
• Email: aartese@fau.edu
• Phone: 856-534-8926

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.