Functional capacity and muscle function in adults with obstructive sleep apnea
Official title: Investigation of Functional Capacity in Patients With Obstructive Sleep Apnea
Run by Karabuk University · NCT07913139 · Data updated 2026-11-12
This study tests how obstructive sleep apnea affects respiratory and peripheral muscle strength, endurance, and upper‑extremity function compared with healthy adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | Karabuk University Academic / other |
| Locations | 1 site (Karabük) |
| Status | Recruiting |
| Started | October 28, 2026 |
| Main results expected | October 28, 2027 |
| Study ends | October 30, 2027 |
| Registry record updated | November 3, 2026 |
| Trial ID | NCT07913139 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–65 with OSAS confirmed by polysomnography and an AHI ≥5 who are willing to participate and do not have major confounding medical conditions.
✕Probably not a fit
People with severe orthopedic, neurological, or cardiac conditions, pulmonary disease, psychiatric or current neurological disorders, or those unwilling to participate may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study compares adults with obstructive sleep apnea to healthy controls to evaluate respiratory function, respiratory muscle strength and endurance, peripheral muscle strength, upper-extremity functional capacity, muscle oxygenation, and dyspnea. Participants aged 18 to 65 with OSAS confirmed by polysomnography and an AHI of 5 or more are assessed and compared to controls without OSAS. Measurements may include pulmonary function tests, muscle strength testing, and functional exercise capacity, along with assessments of muscle oxygenation and breathlessness. The study aims to identify how OSAS affects muscle performance and daily activity, informing potential targets for therapy or rehabilitation.
Why it matters
Potential benefit: If successful, findings could guide rehabilitation strategies to improve breathing efficiency and daily functioning in people with OSAS.
How similar studies have gone: Previous research has explored respiratory function in OSAS, but this study emphasizes a broader set of muscle and functional outcomes and includes healthy controls for comparison.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-65, * Diagnosis of Obstructive Sleep Apnea Syndrome (OSAS) confirmed by a pulmonologist following polysomnography, * An Apnea-Hypopnea Index (AHI) ≥5 for OSAS, * Willingness to participate in the study. Exclusion Criteria: * Having severe orthopedic, neurological, or cardiac conditions, * Having a diagnosed pulmonary disease, * Having a history of-or currently experiencing-a psychiatric or neurological disorder, * Not being willing to participate in the study.
Where it's running
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Karabuk University, Physiotherapy and Rehabilitation Application and Research Center
Karabük, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ebrar Tülümenoğlu, MSc (c) — Karabuk University
- Study coordinator: Musa Güneş, PhD
- Email: musagunes@karabuk.edu.tr
- Phone: 03704789131
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography
Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.
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Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea
This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.
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Transcutaneous Electrical Stimulation for Obstructive Sleep Apnea
This study tests whether applying gentle electrical stimulation to the throat muscles at night can reduce sleep apnea severity in adults with obstructive sleep apnea.
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Physical activity habits and sleep/ breathing in obstructive sleep apnea
This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.
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CES-EES score and a wearable ring for diagnosing obstructive sleep apnea
This study tests whether the CES-EES clinical score and the Belun Ring wearable can accurately diagnose obstructive sleep apnea without in-lab polysomnography in adults referred for suspected OSA.
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Tonsillectomy Added to Hypoglossal Nerve Stimulation for OSA with Lateral Wall Collapse
In adults with obstructive sleep apnea and side-wide airway collapse, this study tests whether adding tonsil removal to hypoglossal nerve stimulation helps more than hypoglossal nerve stimulation alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.