Examining quality of life in thyroid cancer and tumours

Health Related Quality of Life in Thyroid Cancer Patients, and in Patients With Thyroid Nodules Suspicious of Cancer

Observational Oslo University Hospital · NCT03676348

This study looks at how surgery for thyroid cancer and tumors affects the quality of life for patients over time.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorOslo University Hospital Academic / other
Locations1 site (Oslo)
Trial IDNCT03676348 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the quality of life (QOL) in patients undergoing surgery for thyroid tumours and thyroid cancer. Participants will complete validated questionnaires before surgery and at 6 and 12 months post-surgery to evaluate how their QOL is affected by their diagnosis and the surgical intervention. The study will categorize participants into three groups based on their diagnosis: benign tumours, malignant tumours with radioiodine treatment, and malignant tumours without radioiodine treatment. Data will be collected from medical records at Oslo University Hospital to support the findings.

Who should consider this trial

Good fit: Ideal candidates are adults scheduled for hemi- or total thyroidectomy due to suspicious thyroid tumours.

Not a fit: Patients who have had thyroid surgery within the last two years or those unable to complete the questionnaires will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the impact of thyroid cancer and its treatment on patients' quality of life.

How similar studies have performed: Previous studies have indicated that quality of life in thyroid cancer patients may be lower than expected, suggesting that this approach is relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* planned hemi- or total thyroidectomy at the ENT-Department of Oslo University Hospital
* tumour in the thyroid gland With fine needle aspiration results of Bethesda 3-6, or other clinical manifestations suspicious of cancer.
* ability to understand and Complete the quesitionnaires
* informed consent to participation

Exclusion Criteria:

* unable to Complete or understand the questionnaires
* age below 18 years
* thyroid surgery within the last 2 years
* thyroid surgery on other indications than listed above
* participants With postoperative external radiotherapy

Where this trial is running

Oslo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thyroid NoduleThyroid CancerQuality of Lifequality of lifehealth related quality of lifethyroid cancerthyroid nodulethyroid neoplasm
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.