Examining patterns of invasion in oral squamous cell carcinoma
WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA: AN INDEPENDENT PROGNOSTIC INDICATOR
This study looks at how the way oral cancer spreads affects the outcomes for patients to help improve treatment decisions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 81 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Armed Forces Institute of Pathology Rawalpindi Government |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Rawalpindi, Punjab) |
| Trial ID | NCT05927220 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on oral squamous cell carcinoma (OSCC), a common and aggressive form of oral cancer. It aims to evaluate various prognostic histopathological indicators, particularly the patterns of invasion, and their correlation with patient outcomes. The study will analyze biopsy specimens from OSCC patients who have undergone neck dissections, assessing factors such as tumor stage, differentiation, and invasion depth. The findings could enhance understanding of OSCC prognosis and inform treatment decisions.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with oral squamous cell carcinoma who have undergone neck dissections.
Not a fit: Patients who have received chemotherapy or radiotherapy prior to surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve prognostic assessments and treatment strategies for patients with oral squamous cell carcinoma.
How similar studies have performed: Previous studies have indicated the significance of histopathological factors in OSCC prognosis, suggesting that this approach has potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All OSCC patients who underwent neck dissections * Patients from all age groups and both genders Exclusion Criteria: * All specimens with poor fixation * All specimens of patients having received chemotherapy and/or radiotherapy prior to the surgery * Patients not consenting to be the part of study
Where this trial is running
Rawalpindi, Punjab
- Armed Forces Institute of Pathology — Rawalpindi, Punjab, Pakistan (Recruiting)
Study contacts
- Principal investigator: Manahil Rahat, BDS — AFIP Rawalpindi Pakistan
- Study coordinator: Manahal Rahat, BDS
- Email: manahil.khan191993@gmail.com
- Phone: +923335681022
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.