Examining memory and brain changes after aneurysmal subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the long-term neuropsychological effects of aneurysmal subarachnoid hemorrhage (aSAH), particularly focusing on memory deficits and their potential association with hippocampal atrophy. The study will include 29 patients undergoing neurological rehabilitation, who will receive neuropsychological assessments and structural MRI scans within the first week of enrollment. By examining these relationships in the acute phase of recovery, the study aims to clarify the discrepancy between memory impairments and normal structural imaging results. The findings could provide insights into cognitive rehabilitation strategies for affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* neurological rehabilitation patients in phase B - D
* at minimum eight weeks after disease onset
* aneurysmal subarachnoid hemorrhage (Hunt \& Hess grade I or II)
* written consent from the patient's legal representative
* exclusion of pregnancy

Exclusion Criteria:

* insufficient cardiorespiratory stability
* previous brain damage
* mental disorders (dementia, depression)
* colonization with multi-resistant pathogens
* MRI contraindications
* claustrophobia
* weight \> 120 kg

Where it's running

• BDH-Clinic Hessisch Oldendorf
  Hessisch Oldendorf, Germany Recruiting

Study contacts

• Principal investigator: Melanie Boltzmann, PhD — BDH-Clinic Hessisch Oldendorf
• Study coordinator: Melanie Boltzmann, PhD
• Email: m.boltzmann@bdh-klinik-hessisch.oldendorf
• Phone: 0049 5152 781 256

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.