Examining how THC affects men and women differently

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the acute effects of delta-9-tetrahydrocannabinol (THC) on healthy individuals, focusing on gender-related differences. It aims to characterize how men and women respond to THC and to explore the underlying mechanisms of these differences. Participants will receive either THC or a placebo to assess the immediate effects of the substance. The study is designed to enhance understanding of cannabinoid effects across genders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* at least one lifetime exposure to cannabis
* good physical and mental health

Exclusion Criteria:

* cannabis naive individuals
* major current or recent stressors
* taking estrogen supplements or oral contraceptive pills (for women)

Where it's running

• Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine
  West Haven, Connecticut, United States Recruiting

Study contacts

• Study coordinator: Christina Luddy, BS
• Email: christina.luddy@yale.edu
• Phone: 203-932-5711

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.