Examining how different exercise patterns affect obesity and metabolic syndrome in children and adolescents
The Interaction and Regulation Mechanism of Different Exercise Patterns With Metabolic Syndrome and Related Metabolic Diseases
NA · Peking University Third Hospital · NCT04984005
This study is testing how different types of exercise can help children and teens with obesity or metabolic syndrome improve their weight and health.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 366 (estimated) |
| Ages | 8 Years to 16 Years |
| Sex | All |
| Sponsor | Peking University Third Hospital (other) |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT04984005 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of various exercise intensities on children and adolescents diagnosed with obesity or metabolic syndrome in China. Participants are randomly assigned to one of three groups: low intensity, moderate intensity, or intermittent high intensity exercise training. The study aims to evaluate changes in weight and cardiometabolic risk factors, as well as explore the underlying mechanisms through multi-omics analyses, including metabolomics and gut microbiome assessments. The trial utilizes advanced techniques such as abdominal ultrasound and computational fluid dynamics to gather data on organ hydrodynamics.
Who should consider this trial
Good fit: Ideal candidates are children and adolescents diagnosed with obesity or metabolic syndrome who are academically performing well and willing to participate.
Not a fit: Patients with specific conditions like Cushing syndrome or those with pathological obesity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide tailored exercise interventions that significantly improve health outcomes for children and adolescents with obesity and metabolic syndrome.
How similar studies have performed: Other studies have shown promising results with exercise interventions for obesity and metabolic syndrome, suggesting that this approach is both relevant and potentially effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of overweight or obesity or metabolic syndrome; * Good academic performance in school; * Willing to sign informed consent. Exclusion Criteria: * Clinical diagnosis of Cushing syndrome; * Pathological obesity such as Prader-Willi syndrome and obesity caused by drug factors； * Participated in other intervention studies within the previous three months; * participant or their guardian has obvious intellectual or mental abnormalities.
Where this trial is running
Beijing, Beijing
- Peking University Third Hospital — Beijing, Beijing, China (RECRUITING)
Study contacts
- Study coordinator: Haiyi Yu, Dr.
- Email: yuhaiyi@bjmu.edu.cn
- Phone: 0086013466615475
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Obesity, Metabolic Syndrome, children and adolescents, metabolic syndrome, overweight, exercise