Examining hormone levels and insulin resistance in women with PCOS
Changes in Serum, Follicular Fluid SREBP1c and LRG1 Levels in PCOS Patients and Correlation With Insulin Resistance
This study is testing the hormone levels in women with PCOS to see how they relate to insulin resistance and overall metabolic health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 20 Years to 50 Years |
| Sex | Female |
| Sponsor | Zunyi Medical College Academic / other |
| Locations | 1 site (Zunyi, Guizhou) |
| Trial ID | NCT06066034 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on women diagnosed with Polycystic Ovary Syndrome (PCOS) to evaluate the levels of SREBP1c and LRG1 in serum and follicular fluid, and their correlation with insulin resistance. Participants will undergo a series of assessments including blood tests for glucose, lipids, insulin, and sex hormones, as well as the collection of follicular fluid for further analysis. The study aims to enhance understanding of the metabolic aspects of PCOS and how they relate to insulin sensitivity.
Who should consider this trial
Good fit: Ideal candidates for this study are women of childbearing age who have been clinically diagnosed with Polycystic Ovary Syndrome.
Not a fit: Patients with conditions such as congenital adrenal cortical hyperplasia, adrenocortical carcinoma, or Cushing syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the metabolic dysfunctions associated with PCOS, potentially leading to improved management strategies for affected women.
How similar studies have performed: While there have been studies examining insulin resistance in PCOS, the specific focus on SREBP1c and LRG1 levels in this context may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Clinical diagnosis of Polycystic Ovary Syndrome Exclusion Criteria: Congenital adrenal cortical hyperplasia Adrenocortical carcinoma Cushing syndrome.
Where this trial is running
Zunyi, Guizhou
- Affiliated Hospital of Zunyi Medical University — Zunyi, Guizhou, China (Recruiting)
Study contacts
- Principal investigator: Fa Sun — Guizhou Provincial Health Commission
- Study coordinator: Xin LIao, Dr
- Email: liaoxin8618@163.om
- Phone: +86 135 9520 8618
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.