Examining health services and quality of life in patients with atypical Parkinsonian syndromes
Official title: Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes
Run by University Hospital Southampton NHS Foundation Trust · NCT06645626 · Data updated 2026-11-12
This study looks at how people with atypical Parkinsonian syndromes, like progressive supranuclear palsy and multiple system atrophy, use health services and how their quality of life is affected by having access to specialist clinics and support services.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 198 (estimated) |
| Sponsor | University Hospital Southampton NHS Foundation Trust Academic / other |
| Locations | 1 site (Southampton, Hampshire) |
| Status | Recruiting |
| Started | October 10, 2022 |
| Main results expected | August 31, 2026 |
| Study ends | July 15, 2027 |
| Registry record updated | October 17, 2024 |
| Trial ID | NCT06645626 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and over with a diagnosis of progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy.
✕Probably not a fit
Patients with static deficits or those not meeting the inclusion criteria, as well as those with co-morbidities that may hinder participation, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the health care utilization and quality of life of patients diagnosed with progressive supranuclear palsy, corticobasal degeneration, and multiple system atrophy. It compares experiences in regions with specialist clinics to those without, aiming to identify which aspects of care are most beneficial. The study also evaluates the impact of multidisciplinary support services on patients and their caregivers, focusing on improving management and quality of life despite the absence of curative treatments.
Why it matters
Potential benefit: If successful, this study could lead to improved care strategies that enhance the quality of life for patients and their families dealing with atypical Parkinsonian syndromes.
How similar studies have gone: While there is limited research specifically on these atypical syndromes, studies on multidisciplinary care models for other neurological conditions have shown positive outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients and their carers must: * Be aged 18 or over * Have capacity to consent at the beginning of their involvement * Have a diagnosis of a neurodegenerative disease which includes progressive supranuclear palsy, corticobasal syndrome and multiple system atrophy but may include other closely related diseases where the presentation is similar, such as Alzheimer's disease where they present with a corticobasal syndrome Exclusion Criteria: * Patients or carers not meeting the inclusion criteria * Patients with static deficits only who do not have a neurodegenerative syndrome. * Patients who the principal investigator feels are not suitable to take part due to co-morbidities or participation in other trials.
Where it's running
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Wessex Neurological Centre
Southampton, Hampshire, United Kingdom Recruiting
Study contacts
- Principal investigator: Boyd CP Ghosh, MBBS — Wessex Neurological Centre
- Study coordinator: Trial administrator Neurodegenerative research team
- Email: srikanth.anugu@uhs.nhs.uk
- Phone: 0044 2381206132
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.