Examining brain changes in stroke patients during challenging walking tasks
Official title: Neural Mechanism Changes in Stroke Patients During Challenging Environments
Run by Nanjing Medical University · NCT06764290 · Data updated 2026-11-12
This study looks at how different walking challenges affect brain activity in stroke patients to help improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Nanjing Medical University Academic / other |
| Locations | 2 sites (Nanjing, Jiangsu and 1 other locations) |
| Status | Recruiting |
| Started | April 1, 2024 |
| Main results expected | January 30, 2025 |
| Study ends | February 28, 2025 |
| Registry record updated | January 8, 2025 |
| Trial ID | NCT06764290 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are stroke patients who are at least 14 days post-stroke, can walk independently, and have an abnormal gait.
✕Probably not a fit
Patients with lesions in the brainstem or cerebellum, impaired vision, or severe cognitive impairment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how challenging walking tasks, such as pedal walking and walking with eyes covered, affect brain activation in stroke patients. Participants will wear a 32-lead electroencephalogram (EEG) cap while performing three different walking tasks to assess biomechanics and neural mechanisms involved in recovery. The study aims to understand the relationship between task difficulty and brain activation, potentially leading to improved rehabilitation strategies for stroke survivors.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation techniques for stroke patients, promoting better recovery outcomes.
How similar studies have gone: While this approach is innovative, similar studies exploring the effects of challenging tasks on rehabilitation have shown promise, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * First-time occurrence of stroke confirmed by computed tomography or magnetic resonance imagingClinical diagnosis of stroke * Disease duration of more than 14 days, less than 1 year * Able to walk independently but with a lingering abnormal gait Exclusion Criteria: * Lesions accumulate in the brainstem * Lesions accumulate in the cerebellum * Impaired vision * Severe cognitive impairment
Where it's running
-
Geriatric Hospital of Nanjing Medical University, 269 Qingmen Street
Nanjing, Jiangsu, China Recruiting -
Geriatric Hospital of Nanjing Medical University
Nanjing, Jiangsu, China Recruiting
Study contacts
- Study coordinator: Jing Zhao, master
- Email: 18817892579@163.com
- Phone: +8618817892579
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
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Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.