Clinical trial Recruiting at 2 sites Observational Ages 18 to 70

Examining brain changes in stroke patients during challenging walking tasks

Official title: Neural Mechanism Changes in Stroke Patients During Challenging Environments

Run by Nanjing Medical University · NCT06764290 · Data updated 2026-11-12

This study looks at how different walking challenges affect brain activity in stroke patients to help improve their recovery.

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment60 (estimated)
SponsorNanjing Medical University
Academic / other
Locations2 sites (Nanjing, Jiangsu and 1 other locations)
StatusRecruiting
StartedApril 1, 2024
Main results expectedJanuary 30, 2025
Study endsFebruary 28, 2025
Registry record updatedJanuary 8, 2025
Trial IDNCT06764290 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are stroke patients who are at least 14 days post-stroke, can walk independently, and have an abnormal gait.

Probably not a fit

Patients with lesions in the brainstem or cerebellum, impaired vision, or severe cognitive impairment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how challenging walking tasks, such as pedal walking and walking with eyes covered, affect brain activation in stroke patients. Participants will wear a 32-lead electroencephalogram (EEG) cap while performing three different walking tasks to assess biomechanics and neural mechanisms involved in recovery. The study aims to understand the relationship between task difficulty and brain activation, potentially leading to improved rehabilitation strategies for stroke survivors.

Why it matters

Potential benefit: If successful, this study could enhance rehabilitation techniques for stroke patients, promoting better recovery outcomes.

How similar studies have gone: While this approach is innovative, similar studies exploring the effects of challenging tasks on rehabilitation have shown promise, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* First-time occurrence of stroke confirmed by computed tomography or magnetic resonance imagingClinical diagnosis of stroke
* Disease duration of more than 14 days, less than 1 year
* Able to walk independently but with a lingering abnormal gait

Exclusion Criteria:

* Lesions accumulate in the brainstem
* Lesions accumulate in the cerebellum
* Impaired vision
* Severe cognitive impairment

Where it's running

  • Geriatric Hospital of Nanjing Medical University, 269 Qingmen Street
    Nanjing, Jiangsu, China
    Recruiting
  • Geriatric Hospital of Nanjing Medical University
    Nanjing, Jiangsu, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.