Evaluating the long-term safety of the Aveir VR leadless pacemaker

Aveir Single-Chamber Leadless Pacemaker Real-World Evidence Post-Approval Study

Observational Abbott Medical Devices · NCT05270499

This study is testing the long-term safety of the Aveir VR leadless pacemaker in a large group of patients to see how well it works in real life.

Quick facts

Study typeObservational
Enrollment2100 (estimated)
Ages18 Years and up
SexAll
SponsorAbbott Medical Devices Industry-sponsored
Locations1 site (Sylmar, California)
Trial IDNCT05270499 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the long-term safety of the Aveir VR leadless pacemaker by utilizing real-world evidence methods. It is a non-randomized, multi-center study that combines various real-world datasets from Abbott and the Center for Medicare Services to evaluate the safety of the device in a large patient population. The findings will help fulfill the FDA's Condition of Approval requirements for the Aveir VR device.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who have been implanted with an Aveir VR leadless pacemaker and meet specific Medicare enrollment criteria.

Not a fit: Patients who have not received the Aveir VR leadless pacemaker or those who do not meet the Medicare enrollment criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term safety of the Aveir VR leadless pacemaker, potentially improving patient outcomes.

How similar studies have performed: Other studies evaluating leadless pacemakers have shown promising results, indicating that this approach is supported by prior successful research.

Eligibility criteria

Show full inclusion / exclusion criteria
Eligibility Criteria:

* Implanted with an Aveir VR leadless pacemaker
* Continuous enrollment in Medicare Part A and Part B for 12 months prior to implant and for 30 days after implant, except in the case of death within the 30-day period
* Ability to link with Medicare fee-for-service data

Where this trial is running

Sylmar, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiac PacemakerArrythmiaBradycardiabradycardiasick sinus rhythmpacemakerav blockVasovagal Syncope
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.