Evaluating the effects of residual neuromuscular block after surgery

Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications

Observational Dr. Negrin University Hospital · NCT06386354

This study looks at how leftover muscle weakness after surgery affects recovery and complications in patients who were given anesthesia with muscle relaxants.

Quick facts

Study typeObservational
Enrollment296 (estimated)
Ages18 Years and up
SexAll
SponsorDr. Negrin University Hospital Academic / other
Locations2 sites (Las Palmas de Gran Canaria, Las Palmas and 1 other locations)
Trial IDNCT06386354 on ClinicalTrials.gov

What this trial studies

This observational study investigates the occurrence of residual neuromuscular blockade (RNMB) in patients who have undergone general anesthesia with neuromuscular blockers. It aims to assess the impact of RNMB on postoperative complications during hospital admission. By monitoring patients for one month after surgery, the study seeks to identify the prevalence of RNMB and its potential consequences on patient safety and recovery. The methodology includes the use of a train-of-four monitoring technique to evaluate neuromuscular function.

Who should consider this trial

Good fit: Ideal candidates are patients undergoing surgical procedures requiring general anesthesia with neuromuscular blockers who will be admitted to the hospital.

Not a fit: Patients with neuromuscular diseases or those who did not receive neuromuscular blockers during surgery will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance postoperative care by reducing complications associated with residual neuromuscular blockade.

How similar studies have performed: Other studies have indicated the importance of monitoring neuromuscular blockade, suggesting that this approach could yield valuable insights into postoperative outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient undergoing surgical intervention under general anesthesia that requires the use of neuromuscular block during the study time and that required hospital admission.
* Informed consent signature.

Exclusion Criteria:

* Neuromuscular disease
* Not having received neuromuscular block during the intervention
* Admission to the outpatient surgery unit
* Admission to the postoperative intensive care unit
* Patients who signed informed consent, but postoperative data could not be collected upon arrival at the PACU.

Where this trial is running

Las Palmas de Gran Canaria, Las Palmas and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative Neuromuscular BlockPostoperative ComplicationsGeneral AnesthesiaNeuromuscular block
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.