Evaluating the Autonomic Nervous System in Multiple Sclerosis Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study aims to assess the involvement of the autonomic nervous system in patients with relapsing-remitting and primary progressive multiple sclerosis. It seeks to define characteristics of dysautonomia to enhance treatment strategies for managing symptoms like orthostatic hypotension and thermoregulation disorders. The study will utilize skin biopsies to quantify small nerve fibers and conduct cardiovascular reflex testing, alongside clinical scales to evaluate autonomic and pain symptoms. By understanding the correlation between autonomic dysfunction and disease progression, the study hopes to improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of relapsing-remitting and primary progressive multiple sclerosis.

Exclusion Criteria:

* other forms of multiple sclerosis,
* known other neurological disorders
* assumption of potentially neurotoxic substances or drugs.

Where it's running

• ICS Maugeri - IRCCS of Telese Terme
  Telese Terme, Benevento, Italy Recruiting
• Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II
  Naples, Italy Recruiting

Study contacts

• Principal investigator: Vincenzo Provitera, MD — Ics Maugeri - Irccs Telese Terme
• Study coordinator: Vincenzo Provitera, MD
• Email: vincenzo.provitera@icsmaugeri.it
• Phone: +390824909257

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.