Evaluating sleep-disordered breathing in lung transplant patients
Sleep-disordered Breathing After Solid Organ Transplantation
This study looks at how common sleep problems are in people who have had a lung transplant and how these issues relate to their overall health one year after the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven) |
| Trial ID | NCT03142022 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the prevalence and types of sleep-disordered breathing (SDB) in patients who have undergone lung transplantation. It will involve diagnostic polysomnography conducted one year post-transplant to identify the incidence of central and obstructive SDB. Additionally, the study will explore correlations between the severity of SDB and various clinical factors such as weight, heart and lung function, and cardiovascular health. The findings could provide insights into the long-term health challenges faced by lung transplant recipients.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who are one year post-lung transplantation.
Not a fit: Patients who refuse polysomnography or have medical contraindications to the procedure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for sleep-disordered breathing in lung transplant patients, enhancing their quality of life.
How similar studies have performed: While sleep-disordered breathing is a known issue in various populations, this specific focus on lung transplant patients is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 1 year after lung transplantation Exclusion Criteria: * Refusal of PSG * Medical contra-indication to perform PSG
Where this trial is running
Leuven
- UZ Leuven — Leuven, Belgium (Recruiting)
Study contacts
- Principal investigator: Dries Testelmans, MD, PhD — UZ Leuven
- Study coordinator: Dries Testelmans, MD, PhD
- Email: dries.testelmans@uzleuven.be
- Phone: 00 32 16 34 25 22
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.