Evaluating risk factors in twin pregnancies using Doppler echoflowmetry
Official title: Retrospective and Prospective Study on the Role of Doppler Echoflowmetry in Defining Risk Factors for the Development of Complications in Twin Pregnancies
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06782776 · Data updated 2026-11-12
This study is trying to see if new guidelines and regular check-ups can help improve the health and outcomes of women having twins.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 44 Years |
| Sex | Women only |
| Enrollment | 6600 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Status | Recruiting |
| Started | February 8, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | January 20, 2025 |
| Trial ID | NCT06782776 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women over 18 years old with a twin pregnancy who have their ultrasound monitoring and delivery at Policlinico S Orsola in Bologna, Italy.
✕Probably not a fit
Patients who deliver at a different facility or refuse instrumental monitoring will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the outcomes of twin pregnancies at a specialized center to determine if updated guidelines and systematic follow-ups have improved management and reduced complications. It includes both retrospective and prospective data collection from patients monitored at the facility over the past 15 years. Participants will undergo standard ultrasound evaluations along with additional assessments using the USCOM 1A® technique and Doppler ultrasound to evaluate maternal and fetal health. The goal is to gather comprehensive data to enhance counseling and management strategies for twin pregnancies.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for twin pregnancies, potentially reducing complications and enhancing maternal and fetal outcomes.
How similar studies have gone: While similar studies have explored the use of Doppler echoflowmetry in pregnancy, this specific approach focusing on twin pregnancies and long-term outcomes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Twin Pregnancy * Ultrasound monitoring and delivery occurred at Policlinico S Orsola in Bologna, Italy * Written informed consent form obtained from the patient Exclusion Criteria: * Completion of delivery at another facility * Desire to undertake the Voluntary Interruption of Pregnancy * Refusal to undergo instrumental monitoring and subsequent follow-up at our center
Where it's running
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IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy Recruiting
Study contacts
- Principal investigator: Gianluigi Pilu, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Gianluigi Pilu, MD
- Email: gianluigi.pilu@aosp.bo.it
- Phone: 0512143493
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.