Evaluating risk factors in twin pregnancies using Doppler echoflowmetry
Retrospective and Prospective Study on the Role of Doppler Echoflowmetry in Defining Risk Factors for the Development of Complications in Twin Pregnancies
This study is trying to see if new guidelines and regular check-ups can help improve the health and outcomes of women having twins.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6600 (estimated) |
| Ages | 18 Years to 44 Years |
| Sex | Female |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Trial ID | NCT06782776 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the outcomes of twin pregnancies at a specialized center to determine if updated guidelines and systematic follow-ups have improved management and reduced complications. It includes both retrospective and prospective data collection from patients monitored at the facility over the past 15 years. Participants will undergo standard ultrasound evaluations along with additional assessments using the USCOM 1A® technique and Doppler ultrasound to evaluate maternal and fetal health. The goal is to gather comprehensive data to enhance counseling and management strategies for twin pregnancies.
Who should consider this trial
Good fit: Ideal candidates are women over 18 years old with a twin pregnancy who have their ultrasound monitoring and delivery at Policlinico S Orsola in Bologna, Italy.
Not a fit: Patients who deliver at a different facility or refuse instrumental monitoring will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for twin pregnancies, potentially reducing complications and enhancing maternal and fetal outcomes.
How similar studies have performed: While similar studies have explored the use of Doppler echoflowmetry in pregnancy, this specific approach focusing on twin pregnancies and long-term outcomes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Twin Pregnancy * Ultrasound monitoring and delivery occurred at Policlinico S Orsola in Bologna, Italy * Written informed consent form obtained from the patient Exclusion Criteria: * Completion of delivery at another facility * Desire to undertake the Voluntary Interruption of Pregnancy * Refusal to undergo instrumental monitoring and subsequent follow-up at our center
Where this trial is running
Bologna, Bologna
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, Bologna, Italy (Recruiting)
Study contacts
- Principal investigator: Gianluigi Pilu, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Gianluigi Pilu, MD
- Email: gianluigi.pilu@aosp.bo.it
- Phone: 0512143493
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.