Study of Twin Pregnancies and Their Outcomes in China
Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China
This study is trying to understand the challenges and outcomes of twin pregnancies in China by following 2000 pregnant women and their babies from pregnancy through early childhood.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 11 sites (Hefei, Anhui and 10 other locations) |
| Trial ID | NCT06414655 on ClinicalTrials.gov |
What this trial studies
The ChiTwiMC cohort is a multicenter prospective study focusing on the complications associated with twin pregnancies in China. It aims to establish a large mother-child cohort that follows participants from pregnancy through early childhood, collecting extensive data on maternal and neonatal outcomes. The study will recruit 2000 pregnant women aged 18-45 years from nine major university-affiliated hospitals, with data collection occurring at various stages of pregnancy and after delivery. Biological samples will also be collected to investigate adverse outcomes related to twin pregnancies.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18-45 years who are expecting twins and are less than 14 weeks pregnant.
Not a fit: Patients with serious maternal illnesses or mental disorders that prevent participation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve understanding and management of complications in twin pregnancies, leading to better maternal and neonatal health outcomes.
How similar studies have performed: While there have been studies on twin pregnancies, this specific multicenter approach with a comprehensive biobank is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Twin pregnancies * Female aged between 18-45 years * Gestational age is less than 14 weeks * Planning to receive prenatal healthcare and delivery service at the study hospital * Signing informed concent and willing to participate Exclusion Criteria: * Women with mental disorders or serious maternal illness that is not eligible to participate * Inability to provide informed consent * Pregnant women not registered in our hospital
Where this trial is running
Hefei, Anhui and 10 other locations
- The First Affiliated Hospital of Anhui Medical University — Hefei, Anhui, China (Recruiting)
- Peking University Third Hospital — Beijing, Beijing Municipality, China (Recruiting)
- Peking University — Beijing, Beijing Municipality, China (Recruiting)
- Chongqing Medical University — Chongqing, Chongqing Municipality, China (Recruiting)
- First Affiliated Hospital, Sun Yat-Sen University — Guangzhou, Guangdong, China (Recruiting)
- Shengjing Hospital — Shenyang, Liaoning, China (Recruiting)
- Shandong Provincial Hospital — Jinan, Shandong, China (Recruiting)
- The Second Hospital of Shandong University — Jinan, Shandong, China (Recruiting)
- International Peace Maternity and Child Health Hospital — Shanghai, Shanghai Municipality, China (Recruiting)
- Shanghai First Maternity and Infant Hospital — Shanghai, Shanghai Municipality, China (Recruiting)
- Nankai University — Tianjin, Tianjin Municipality, China (Recruiting)
Study contacts
- Study coordinator: Yuan Wei, PhD, MD
- Email: weiyuanbysy@163.com
- Phone: 01082267852
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.