Study of Twin Pregnancies and Their Outcomes in China
Official title: Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China
Run by Peking University Third Hospital · NCT06414655 · Data updated 2026-11-12
This study is trying to understand the challenges and outcomes of twin pregnancies in China by following 2000 pregnant women and their babies from pregnancy through early childhood.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 2000 (estimated) |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 11 sites (Hefei, Anhui and 10 other locations) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | May 16, 2024 |
| Trial ID | NCT06414655 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18-45 years who are expecting twins and are less than 14 weeks pregnant.
✕Probably not a fit
Patients with serious maternal illnesses or mental disorders that prevent participation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The ChiTwiMC cohort is a multicenter prospective study focusing on the complications associated with twin pregnancies in China. It aims to establish a large mother-child cohort that follows participants from pregnancy through early childhood, collecting extensive data on maternal and neonatal outcomes. The study will recruit 2000 pregnant women aged 18-45 years from nine major university-affiliated hospitals, with data collection occurring at various stages of pregnancy and after delivery. Biological samples will also be collected to investigate adverse outcomes related to twin pregnancies.
Why it matters
Potential benefit: If successful, this study could improve understanding and management of complications in twin pregnancies, leading to better maternal and neonatal health outcomes.
How similar studies have gone: While there have been studies on twin pregnancies, this specific multicenter approach with a comprehensive biobank is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Twin pregnancies * Female aged between 18-45 years * Gestational age is less than 14 weeks * Planning to receive prenatal healthcare and delivery service at the study hospital * Signing informed concent and willing to participate Exclusion Criteria: * Women with mental disorders or serious maternal illness that is not eligible to participate * Inability to provide informed consent * Pregnant women not registered in our hospital
Where it's running
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The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China Recruiting -
Peking University Third Hospital
Beijing, Beijing Municipality, China Recruiting -
Peking University
Beijing, Beijing Municipality, China Recruiting -
Chongqing Medical University
Chongqing, Chongqing Municipality, China Recruiting -
First Affiliated Hospital, Sun Yat-Sen University
Guangzhou, Guangdong, China Recruiting -
Shengjing Hospital
Shenyang, Liaoning, China Recruiting
Show 5 more locations
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Shandong Provincial Hospital
Jinan, Shandong, China Recruiting -
The Second Hospital of Shandong University
Jinan, Shandong, China Recruiting -
International Peace Maternity and Child Health Hospital
Shanghai, Shanghai Municipality, China Recruiting -
Shanghai First Maternity and Infant Hospital
Shanghai, Shanghai Municipality, China Recruiting -
Nankai University
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Yuan Wei, PhD, MD
- Email: weiyuanbysy@163.com
- Phone: 01082267852
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.