Risk factors for outcomes after surgery for very large intrathoracic tumors
Official title: Risk Factors for Postoperative Outcomes and Complications in Patients With Large Intrathoracic Tumors: A Multicenter Analysis
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT07926490 · Data updated 2026-11-12
This study tests how patients with very large chest tumors fare after surgical removal, to see which factors are linked to better or worse outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Status | Recruiting |
| Started | November 30, 2025 |
| Main results expected | May 30, 2027 |
| Study ends | May 30, 2027 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07926490 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) with intrathoracic tumors ≥5 cm undergoing planned complete surgical resection, excluding NSCLC, thymomas, and wall sarcomas.
✕Probably not a fit
Patients with intrathoracic tumors outside the study criteria or those not undergoing surgery may not benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multicenter observational study focusing on adults with intrathoracic tumors at least 5 cm in size who undergo aiming-for-complete resection. It aims to identify risk factors and postoperative complications by analyzing data across centers. The goal is to improve understanding of which patients are more likely to have favorable or adverse outcomes after surgery for large chest tumors. The study will not assign treatments but will collect and analyze real-world surgical results. Findings could inform surgical planning and patient counseling.
Why it matters
Potential benefit: If successful, the study could help doctors predict risks and tailor perioperative care for patients with large intrathoracic tumors.
How similar studies have gone: Prior reports on this topic are limited and largely case-based; this multicenter analysis seeks to provide more reliable evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Intrathoracic tumors ≥ 5 cm in size * Tumors with either benign or malignant histology * Tumors treated surgically with the aim of complete resection Exclusion Criteria: * NSCLC * Thymomas * Wall sarcomas
Where it's running
-
IRCSS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy Recruiting
Study contacts
- Study coordinator: Pietro Bertoglio, MD
- Email: pietro.bertoglio@aosp.bo.it
- Phone: 0516478362
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.