Clinical trial Recruiting at 1 site Observational Ages 18 and up

Risk factors for outcomes after surgery for very large intrathoracic tumors

Official title: Risk Factors for Postoperative Outcomes and Complications in Patients With Large Intrathoracic Tumors: A Multicenter Analysis

Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT07926490 · Data updated 2026-11-12

This study tests how patients with very large chest tumors fare after surgical removal, to see which factors are linked to better or worse outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Academic / other
Locations1 site (Bologna, Bologna)
StatusRecruiting
StartedNovember 30, 2025
Main results expectedMay 30, 2027
Study endsMay 30, 2027
Registry record updatedNovember 9, 2026
Trial IDNCT07926490 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with intrathoracic tumors ≥5 cm undergoing planned complete surgical resection, excluding NSCLC, thymomas, and wall sarcomas.

Probably not a fit

Patients with intrathoracic tumors outside the study criteria or those not undergoing surgery may not benefit from the findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter observational study focusing on adults with intrathoracic tumors at least 5 cm in size who undergo aiming-for-complete resection. It aims to identify risk factors and postoperative complications by analyzing data across centers. The goal is to improve understanding of which patients are more likely to have favorable or adverse outcomes after surgery for large chest tumors. The study will not assign treatments but will collect and analyze real-world surgical results. Findings could inform surgical planning and patient counseling.

Why it matters

Potential benefit: If successful, the study could help doctors predict risks and tailor perioperative care for patients with large intrathoracic tumors.

How similar studies have gone: Prior reports on this topic are limited and largely case-based; this multicenter analysis seeks to provide more reliable evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Intrathoracic tumors ≥ 5 cm in size
* Tumors with either benign or malignant histology
* Tumors treated surgically with the aim of complete resection

Exclusion Criteria:

* NSCLC
* Thymomas
* Wall sarcomas

Where it's running

  • IRCSS Azienda Ospedaliero-Universitaria di Bologna
    Bologna, Bologna, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.