Evaluating radiosurgery for treating trigeminal neuralgia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study assesses the outcomes of patients with classical trigeminal neuralgia who are treated using high dose rate radiosurgery on a LINAC machine. Conducted at the Centre Hospitalier Princesse Grace, the study includes both retrospective and prospective case series from April 2018 to January 2028. Patients will receive a frameless technique delivering 90 Gy to the intra cisternal portion of the trigeminal nerve, focusing on pain relief and sensory changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Classical trigeminal neuralgia according the International Classification of Headache Disorders
* Trigeminal neuralgia resistant to the maximum tolerated medical therapy, with pain intensity according to the Barrow Neurological Institute (BNI) score IV or V.
* Patients aged \> 18

Exclusion Criteria:

* Patients suffering from secondary Trigeminal neuralgia (tumour in the cerebellopontine angle, arteriovenous malformation or multiple sclerosis)
* Previous history of radiosurgery procedure

Where it's running

• Centre Hospitalier Princesse Grace
  Monaco, Monaco Recruiting

Study contacts

• Study coordinator: Cecile ORTHOLAN, MD
• Email: cecile.ortholan@chpg.mc
• Phone: 00 377 97 98 84 16

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Exploring the link between emotion, memory, and chronic facial pain

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.