Evaluating quality of life after treatment for rectal cancer
Official title: Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer
Run by Ludwig-Maximilians - University of Munich · NCT03731130 · Data updated 2026-11-12
This study looks at how treatment for rectal cancer affects the quality of life for patients who receive radiation or chemotherapy before surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Ludwig-Maximilians - University of Munich Academic / other |
| Drugs / interventions | Radiation |
| Locations | 1 site (Munich, Bavaria) |
| Status | Recruiting |
| Started | October 5, 2018 |
| Main results expected | December 31, 2021 |
| Study ends | December 31, 2026 |
| Registry record updated | November 6, 2018 |
| Trial ID | NCT03731130 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with histologically proven rectal cancer who are eligible for neoadjuvant radiation or chemoradiation therapy.
✕Probably not a fit
Patients under 18 years old, those with distant metastases, or those who have received prior systemic therapy for rectal cancer may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the quality of life in patients with rectal cancer who undergo neoadjuvant radiation or chemoradiation followed by surgery. It will utilize standardized EORTC questionnaires to evaluate longitudinal quality of life, functional outcomes, oncological outcomes, and toxicity. The study will track both acute and late side effects of treatment and analyze correlations between physician and patient-reported outcomes.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the quality of life and treatment outcomes for rectal cancer patients, potentially guiding future treatment approaches.
How similar studies have gone: Other studies have successfully evaluated quality of life in cancer patients using similar methodologies, indicating that this approach is well-established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * histologically proven rectal Cancer without distant metastases * indication for neoadjuvant Radiation or chemoradiation therapy according to multidiciplinary Evaluation * age \>=18 years * written informed consent * ability to answer the standardized questionaires according to the treating physician Exclusion Criteria: * age \< 18 years * prior systemic therapy with regard to rectal Cancer * distant metastasis * second malignancy
Where it's running
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Department of Radiation Oncology, University Hospital, LMU Munich
Munich, Bavaria, Germany Recruiting
Study contacts
- Principal investigator: Falk Roeder, MD — Ludwig-Maximilians Universität München
- Study coordinator: Falk Roeder, MD
- Email: Falk.Roeder@t-online.de
- Phone: +49 89 4400
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.