Condition

Neoadjuvant clinical trials and research

• 6Clinical trials
• 2Countries

Newest Neoadjuvant clinical trials

All recruiting trials (6)

• Ivonescimab with albumin‑paclitaxel and cisplatin before surgery for esophageal squamous cell carcinoma

  This trial tests whether adding ivonescimab to albumin‑paclitaxel and cisplatin before surgery helps people with resectable, locally advanced esophageal squamous cell carcinoma.

  Recruiting Phase 1/2 Tang-Du Hospital · Xi'an, Shannxi · NCT07385001

• Combining carboplatin with mirvetuximab soravtansine before surgery for FRα-positive advanced serous ovarian, fallopian tube, or primary peritoneal cancer

  This will test whether giving mirvetuximab soravtansine with carboplatin before surgery helps people with newly diagnosed FRα-positive advanced-stage serous ovarian, fallopian tube, or primary peritoneal cancer.

  Recruiting at 71 sites Phase 2 AbbVie · Birmingham, Alabama and 72 other locations · NCT06890338

• Neoadjuvant treatment for ER+/HER2+ breast cancer using a combination of drugs

  This study is testing a new combination of drugs to see if it helps women with early or locally advanced HER2-positive breast cancer shrink their tumors before surgery.

  Recruiting at 2 sites Phase 2 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei and 1 other locations · NCT06000917

• Combining Axitinib and PD-1 to Improve Outcomes in Kidney Cancer

  This study is testing if a combination of axitinib and PD-1 therapy can help kidney cancer patients who are at high risk of their cancer coming back after surgery.

  Recruiting at 8 sites Phase 3 Sun Yat-sen University · Beijing and 7 other locations · NCT05738694

• Combination therapy for high-risk acral melanoma before surgery

  This study is testing a new combination of treatments before surgery to see if it can help people with high-risk acral melanoma have better outcomes.

  Recruiting Phase 2 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT05512481

• Using Imatinib Mesylate before surgery for gastrointestinal stromal tumors

  This study is testing if taking imatinib mesylate before surgery can help people with high-risk gastrointestinal stromal tumors have better outcomes and live longer.

  Recruiting Phase 2 First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT04933669

Related topics

Quick answers

How many Neoadjuvant clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (5 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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