Evaluating Pulse Wave Velocity Changes in Stroke Patients After Rehabilitation
Official title: The Improvement in Pulse Wave Velocity and Its Correlation With Clinical Outcomes in Subacute Stroke Patients Following Rehabilitation
Run by Shin Kong Wu Ho-Su Memorial Hospital · NCT06224517 · Data updated 2026-11-12
This study is testing how four weeks of rehabilitation affects blood vessel stiffness in stroke patients to see if it helps them recover better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 25 (estimated) |
| Sponsor | Shin Kong Wu Ho-Su Memorial Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | February 15, 2025 |
| Study ends | June 30, 2025 |
| Registry record updated | February 25, 2025 |
| Trial ID | NCT06224517 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals who have experienced their first ischemic stroke within the last three months and can provide informed consent.
✕Probably not a fit
Patients with hemorrhagic strokes, concurrent neurological diseases, or significant limb deficiencies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the changes in brachial-ankle pulse wave velocity (baPWV) following four weeks of intensive rehabilitation therapy in patients who have experienced a subacute ischemic stroke. It will explore the correlation between these changes in arterial stiffness and the functional recovery of upper limb function. The study will enroll 25 patients at Shin-Kong Wu Ho Su Memorial Hospital, collecting demographic and clinical data to analyze the relationship between PWV and recovery outcomes. The findings could provide insights into the role of arterial stiffness in post-stroke rehabilitation.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation strategies for stroke patients by linking arterial stiffness to functional recovery.
How similar studies have gone: While previous studies have indicated the prognostic value of baPWV in stroke recovery, this specific correlation in subacute stroke patients remains underexplored, making this approach novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * First-onset cerebral ischemic stroke within the previous 3 months, which is confirmed clinically by computed tomography scans or magnetic resonance imaging * Sufficient cognition to understand procedures and provide informed consent. Exclusion Criteria: * Hemorrhagic stroke, cerebellar or brainstem lesions which may affect autonomic or balance * Concurrent neurological or neurodegenerative diseases (e.g. Parkinson's disease, multiple sclerosis, etc.) * Brain tumor * Malignancy * Limb deficiency or amputation
Where it's running
-
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Ying-Chen Kuo, MD — Shin Kong Wu Ho-Su Memorial Hospital
- Study coordinator: Ying-Chen Kuo, MD
- Email: allazure1121@gmail.com
- Phone: +886-952848997
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.