Evaluating new MRI techniques for lymphedema
Official title: Development and Optimization of Novel MRI Techniques on Evaluation of Therapeutic Effects for Lymphedema Secondary to Breast Cancer Treatment: An Integrated Study of Pre-clinical Animal Models and Clinical Follow-up
Run by National Taiwan University Hospital · NCT05804643 · Data updated 2026-11-12
This study is testing new MRI techniques to better understand and track lymphedema in breast cancer patients to improve their treatment outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 210 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | April 10, 2023 |
| Main results expected | December 2024 |
| Study ends | December 2026 |
| Registry record updated | April 19, 2023 |
| Trial ID | NCT05804643 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with breast cancer-related lymphedema.
✕Probably not a fit
Patients under 20 years old, pregnant individuals, or those with contraindications for MRI will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates advanced imaging methods for assessing breast cancer-related lymphedema. It includes three sub-projects: one focuses on developing a pre-clinical rat model and novel MRI techniques, another optimizes clinical MRI methods for mapping lymphedema severity, and the third evaluates post-surgical therapeutic effects. The study aims to create a comprehensive imaging database for future reference and improve the understanding of lymphedema treatment outcomes through longitudinal monitoring.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and monitoring tools for patients with lymphedema, enhancing treatment outcomes.
How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving imaging techniques for lymphedema assessment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adults with breast cancer related lymphedema Exclusion Criteria: * children younger than 20 years old * pregnancy * patients who have absolute contraindications regarding MRI scanning: 1. The cardiac implantable electronic device (CIED) such as pacemakers, implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) devices. 2. Metallic intraocular foreign bodies. 3. Implantable neurostimulation systems 4. Cochlear implants/ear implant: bone-anchored hearing aid (BAHA) cochlear implant type can be scanned on a 1.5-tesla scanner only after the patient removes the battery. Cochlear implant wrapping scheduling must take place before the patient's MRI appointment. 5. Drug infusion pumps (insulin delivery, analgesic drugs, or chemotherapy pumps): If possible, the patient has to remove the device. 6. Catheters with metallic components (Swan-Ganz catheter) 7. Metallic fragments such as bullets, shotgun pellets, and metal shrapnel 8. Cerebral artery aneurysm clips 9. Magnetic dental implants 10. Tissue expander 11. Artificial limb 12. Hearing aid
Where it's running
-
National Taiwan university hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Li-Wei Kuo, Ph.D. — National Health Research Institutes, Taiwan
- Study coordinator: Yeefan Lee, MD
- Email: yeefanlee@ntu.edu.tw
- Phone: +886-972653172
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparing lymphaticovenous anastomosis to sham surgery for cancer-related lymphedema
This study is testing if a new surgery for cancer-related lymphedema can help people feel better compared to a fake surgery.
-
Screening for Breast Cancer-Related Lymphedema in Targeted Therapy
This study tests whether targeted breast cancer therapies are linked to lymphedema by tracking arm volume and symptoms in women undergoing treatment.
-
AI-assisted home-based mood diary for kids with ADHD
A home-based program uses an AI-assisted diary that turns daily mood entries into comic strips to see if it helps kids with ADHD improve emotion regulation.
-
Probiotic supplement BRCAS-C3 and its effect on androgen levels
This pilot study tests whether taking Bacillus coagulans BRCAS-C3 daily for 24 weeks can safely lower or alter androgen levels in healthy adults.
-
Biomarkers that predict medication-related side effects in children with ADHD
This study tests whether combined brain, cognitive, and metabolite markers can predict side effects from methylphenidate in kids with ADHD.
-
Daily-life Virtual Reality Training to Support Thinking and Daily Tasks in adults 50 and older
A touchscreen-based daily-life VR program is being tested to see if it helps people 50+ improve daily activities and thinking skills, especially for those at risk of dementia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.