Clinical trial Recruiting at 1 site Interventional Ages 18 to 65 Women only

Evaluating muscle loss in menopausal women with and without hormone therapy

Official title: Evaluation of Sarcopenia in Women in Different Stages of Life and in Hormonal Therapy or Not

Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06792201 · Data updated 2026-11-12

This study is trying to see if hormone therapy helps menopausal women keep their muscle strength and mass compared to those who don’t use it and to pre-menopausal women.

More Sarcopenia trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexWomen only
Enrollment180 (estimated)
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Academic / other
Locations1 site (Bologna)
StatusRecruiting
StartedJune 14, 2021
Main results expectedJune 14, 2025
Study endsJune 14, 2026
Registry record updatedJanuary 24, 2025
Trial IDNCT06792201 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are menopausal women who are either receiving hormone replacement therapy or not, as well as pre-menopausal women of similar age.

Probably not a fit

Patients who are not menopausal or pre-menopausal women may not receive any benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study aims to assess the prevalence of sarcopenia in menopausal women, comparing those receiving hormone replacement therapy (HRT) to those not receiving it, as well as to pre-menopausal women. Participants will be divided into three groups based on their menopausal status and hormone therapy usage. The study will utilize various assessment methods, including the SARC-F questionnaire, handgrip test, chair stand test, and bioimpedance analysis, to evaluate muscle strength and mass. Data will be collected through health records and physical examinations during outpatient visits.

Why it matters

Potential benefit: If successful, this study could provide insights into the effectiveness of hormone therapy on muscle health in menopausal women.

How similar studies have gone: Other studies have explored sarcopenia in relation to hormonal therapy, indicating that this approach has been previously investigated but may still yield novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients attending the O.U. of Gynecology and Pathophysiology of Human Reproduction in menopause who take or do not take hormone replacement therapy at the time of visit as normal clinical practice and women in pre-menopause.

Patients for whom informed consent has been obtained.

Exclusion Criteria:

* no exclusion criteria are provided

Where it's running

  • IRCCS Azienda Ospedaliero-Universitaria Bologna
    Bologna, Italy
    Recruiting

Study contacts

  • Principal investigator: Maria C Meriggiola — IRCCS Azienda Ospedaliero-Universitaria di Bologna
  • Study coordinator: Giulia Gava, MD
  • Email: gava.giulia@hotmail.it
  • Phone: 0512143716

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.