Evaluating lung ultrasound after surfactant treatments in preterm babies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how different methods of surfactant administration affect lung ultrasound findings in preterm infants diagnosed with respiratory distress syndrome (RDS). Conducted in a neonatal intensive care unit, the research utilizes lung ultrasound as a diagnostic tool, which has become increasingly popular due to its high specificity and sensitivity. The study aims to compare the outcomes of surfactant treatments administered through endotracheal tubes versus less invasive methods. By monitoring serial lung ultrasound data, the study seeks to enhance understanding of treatment efficacy in this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infants of families who agree to participate in the study
* Preterm infants born before 32 weeks of gestation requiring surfactant therapy due to an RDS diagnosis.

Exclusion Criteria:

* Infants whose families did not provide consent
* Infants with a syndromic appearance or congenital heart disease
* Preterm infants born after 32 weeks of gestation

Where it's running

• Melek Buyukeren
  Konya, Karatay, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Melek Buyukeren — Konya City Hospital
• Study coordinator: Melek Buyukeren
• Email: melekbuyukeren@gmail.com
• Phone: +903323105000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• LISA versus endotracheal surfactant distribution in preterm babies

  This pilot trial tests whether giving surfactant through a thin catheter (LISA) or through a breathing tube leads to more even surfactant spread in preterm infants with respiratory distress.

  Recruiting Hamad General Hospital · Doha · NCT07514481

• Lung ultrasound score to guide surfactant timing in preterm newborns

  This study tests whether using a lung ultrasound score can speed up diagnosing severe RDS and getting surfactant to moderately and late-preterm babies in the NICU.

  Recruiting Hackensack Meridian Health · Hackensack, New Jersey · NCT07442669

• Predicting which newborns in a lower-level NICU will need extended breathing support

  This project will test whether analyzing a newborn's stomach fluid right after birth can help predict which babies born at 32+ weeks and attended by the neonatal resuscitation team will need breathing support for more than six hours.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07344714

• Optimising breathing support at extubation for very preterm infants

  This trial will try starting nasal CPAP before removing the breathing tube versus starting it after extubation to see if that reduces oxygen drops in very preterm infants.

  Recruiting at 3 sites Murdoch Childrens Research Institute · Melbourne, Victoria and 2 other locations · NCT07251790

• Using ultrasound to guide surfactant therapy for preterm infants with breathing difficulties

  This study is testing if using ultrasound to help give surfactant treatment can improve breathing for preterm infants with respiratory problems compared to the usual methods.

  Recruiting Connecticut Children's Medical Center · Hartford, Connecticut · NCT06446453

• Minimally invasive surfactant treatment for preterm infants

  This study is testing if giving a special lung treatment right after birth using a gentle method can help very premature babies breathe better compared to waiting until they need extra oxygen.

  Recruiting Phase 4 Endeavor Health · Evanston, Illinois · NCT06007547

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.