Condition

Surfactant clinical trials and research

• 5Clinical trials
• 12Countries

Newest Surfactant clinical trials

All recruiting trials (5)

• Comparing calfactant and poractant alfa delivered by a less invasive catheter to treat respiratory distress in very preterm infants

  This will see if poractant alfa or calfactant given through a thin catheter (LISA) helps preterm infants under 30 weeks with respiratory distress who are breathing on noninvasive support.

  Recruiting at 5 sites Phase 4 Uludag University · Bursa and 4 other locations · NCT07350018

• Amnioinfusion to Protect Newborns After Meconium in Amniotic Fluid

  This trial tests whether a structured lactated Ringer's amnioinfusion during labor can reduce breathing problems and related complications in babies whose amniotic fluid contains meconium.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT07274527

• Duration of surfactant administration: 1 minute vs 5 minutes in very preterm babies

  This trial tests whether giving surfactant over 1 minute or 5 minutes during the LISA procedure helps stabilize cerebral and overall oxygen levels in extremely preterm infants.

  Recruiting Phase 4 Medical University of Graz · Graz · NCT07261787

• SalSA vs LISA: Surfactant Delivery in Preterm Infants

  This study tests whether giving surfactant through SALSA (a supraglottic airway) is safer and more effective than the LISA thin-catheter method in babies born at 29-36 weeks who need help breathing.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07030270

• Comparing video laryngoscopy and direct laryngoscopy for surfactant administration in newborns

  This study is testing whether using video laryngoscopy makes it easier to insert a breathing tube for surfactant treatment in newborns with breathing problems compared to the standard method.

  Recruiting at 14 sites University College Dublin · Rijeka and 15 other locations · NCT06758492

Related topics

Quick answers

How many Surfactant clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (2 trials), Turkey (Türkiye) (1 trial), Austria (1 trial), Croatia (1 trial), Czechia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →