Evaluating lung therapies for patients after heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the effectiveness of three different hyperinflation respiratory therapies—Intermittent Positive Pressure Breathing (IPPB), Intermittent positive end expiratory pressure (EzPAP), and Metaneb—in improving lung recovery in patients following cardiac surgery. Participants will be randomly assigned to one of the therapies to determine which method enhances lung expansion and reduces postoperative respiratory complications. The study focuses on patients recovering from procedures such as coronary artery bypass grafting and valve repairs, where lung expansion is critical to prevent issues like atelectasis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 years and older
2. Admitted to Cardiovascular ICU (CVICU) after coronary artery bypass grafting (CABG), isolated valve repair/replacement, or CABG + valve repair/replacement
3. Cardiac surgery performed via median sternotomy

Exclusion Criteria:

1. BMI\>40
2. Refusal to be consented
3. Prior or current lung transplant patients

Where it's running

• UT Southwestern Clements University Hospital
  Dallas, Texas, United States Recruiting

Study contacts

• Study coordinator: Jaffer Odeh, MD
• Email: Jaffer.Odeh@UTSouthwestern.edu
• Phone: 214-786-1067

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.