Evaluating long-span fixed partial dentures for replacing missing teeth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the clinical performance of long-span fixed partial dentures (FPDs) made from high-strength all-ceramics, specifically zirconia, compared to traditional metal-ceramic FPDs. The study aims to assess the effectiveness and reliability of monolithic and partially veneered zirconia restorations in replacing two adjacent missing posterior teeth. Participants will be monitored over a three-year period to evaluate the durability and aesthetic outcomes of these dental restorations. The trial addresses a gap in existing research regarding the performance of all-ceramic FPDs in clinical settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The patient is at least 18 years old.
* The patient has unrestricted legal capacity.
* The patient has two posterior teeth (premolars and / or molars) that are to be replaced next to each other.
* The patient is reliable and willing to take part in follow-up examinations regularly and over the entire study period (three years).
* The information about the study has been understood by the patient and the signed declaration of consent has been received.

Exclusion Criteria:

* Pregnancy and lactation
* Local and / or systemic acute and / or chronic (also in the past) general medical diseases and conditions that contradict participation in the study and / or expose the patient to a higher risk in the case of participation in the study.
* Severe bruxism diagnosed by a portable electrocardiomyography device (BruxOff) (\> 4 bruxism episodes / night)
* Reduced clinical crown height (\< 5 mm before tooth preparation)
* Limited periodontal health:

  * probing depths \> 4 mm or = 4 mm and bleeding on probing,
  * Furcation involvement \> I (first band of the periodontometer after Naber disappears completely)
  * Degree of loosening of the abutment teeth \> Grade I (\> 1 mm horizontal mobility)
* Untreated endodontic problems of abutment teeth
* Lack of antagonistic support from fixed dentures or natural teeth
* Known allergies or intolerances to the materials used in the study
* Lack of oral hygiene
* Lack of compliance
* Planned change of residence
* Rejection of randomisation

Where it's running

• Department of Prosthodontics, University Hospital Heidelberg, University of Heidelberg
  Heidelberg, Baden-Wurttemberg, Germany Recruiting

Study contacts

• Principal investigator: Wolfgang Bömicke, PD Dr. MSc. — Department of Prosthodontics, University Hospital Heidelberg, University of Heidelberg
• Study coordinator: Wolfgang Bömicke, PD Dr. MSc.
• Email: Wolfgang.Boemicke@med.uni-heidelberg.de
• Phone: +496221566052

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.