Evaluating imaging methods for detecting endoleaks in aortic patients
Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis
This study is testing three different imaging methods to see which one works best for finding leaks in the blood vessels of patients who have had surgery to repair an aortic aneurysm.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 69 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Trial ID | NCT06318780 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of three imaging techniques—dynamic CT angiography (d-CTA), contrast-enhanced ultrasound (CEUS), and traditional three-phase CT angiography—in identifying and characterizing endoleaks in patients who have undergone endovascular aneurysm repair (EVAR). Given the significant risk of endoleaks post-EVAR, which can lead to serious complications, the study aims to improve diagnostic accuracy and patient outcomes. Participants will be monitored for endoleaks and aneurysmal sac enlargement, with a focus on enhancing current imaging protocols.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who have undergone EVAR and exhibit signs of endoleak or significant aneurysmal sac enlargement.
Not a fit: Patients without endoleaks or those whose aneurysmal sac has not enlarged significantly over the specified period may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved detection and management of endoleaks, reducing the risk of complications for patients with aortic endoprostheses.
How similar studies have performed: While there is ongoing research in imaging techniques for endoleaks, this specific combination of d-CTA and CEUS in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 18 years of age and older, * Patients who have received EVAR , * Detection of endoleak and/or with an aneurysmal sac enlargement greater than or equal to 5 mm over 6 months. Exclusion Criteria: * Minor patients, * absence of endoleak and growth of the aneurysmal sac (greater than or equal to 5 mm over 6 months), * patient under guardianship, curators, safeguard of justice, * patient deprived of liberty, * pregnant woman * Patient who does not benefit from a social security scheme
Where this trial is running
Amiens, Picardie
- CHU Amiens Picardie — Amiens, Picardie, France (Recruiting)
Study contacts
- Study coordinator: Thierry REIX, Pr
- Email: reix.thierry@chu-amiens.fr
- Phone: 03.22.08.72.65
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.