Evaluating imaging methods for detecting endoleaks in aortic patients
Official title: Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis
Run by Centre Hospitalier Universitaire, Amiens · NCT06318780 · Data updated 2026-11-12
This study is testing three different imaging methods to see which one works best for finding leaks in the blood vessels of patients who have had surgery to repair an aortic aneurysm.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 69 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Status | Recruiting |
| Started | February 28, 2024 |
| Main results expected | February 2029 |
| Study ends | February 2031 |
| Registry record updated | May 25, 2025 |
| Trial ID | NCT06318780 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who have undergone EVAR and exhibit signs of endoleak or significant aneurysmal sac enlargement.
✕Probably not a fit
Patients without endoleaks or those whose aneurysmal sac has not enlarged significantly over the specified period may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of three imaging techniques—dynamic CT angiography (d-CTA), contrast-enhanced ultrasound (CEUS), and traditional three-phase CT angiography—in identifying and characterizing endoleaks in patients who have undergone endovascular aneurysm repair (EVAR). Given the significant risk of endoleaks post-EVAR, which can lead to serious complications, the study aims to improve diagnostic accuracy and patient outcomes. Participants will be monitored for endoleaks and aneurysmal sac enlargement, with a focus on enhancing current imaging protocols.
Why it matters
Potential benefit: If successful, this study could lead to improved detection and management of endoleaks, reducing the risk of complications for patients with aortic endoprostheses.
How similar studies have gone: While there is ongoing research in imaging techniques for endoleaks, this specific combination of d-CTA and CEUS in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 18 years of age and older, * Patients who have received EVAR , * Detection of endoleak and/or with an aneurysmal sac enlargement greater than or equal to 5 mm over 6 months. Exclusion Criteria: * Minor patients, * absence of endoleak and growth of the aneurysmal sac (greater than or equal to 5 mm over 6 months), * patient under guardianship, curators, safeguard of justice, * patient deprived of liberty, * pregnant woman * Patient who does not benefit from a social security scheme
Where it's running
-
CHU Amiens Picardie
Amiens, Picardie, France Recruiting
Study contacts
- Study coordinator: Thierry REIX, Pr
- Email: reix.thierry@chu-amiens.fr
- Phone: 03.22.08.72.65
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.