Evaluating eye movements and training for stroke patients
Official title: Eye-movement Dynamics During Free Viewing as a Biomarker for Assessment of Visuospatial Functions and for Closed-loop Rehabilitation in Stroke
Run by IRCCS San Camillo, Venezia, Italy · NCT06965673 · Data updated 2026-11-12
This study tests whether tracking eye movements can help understand vision problems in stroke patients and if a new training program using sound can improve their visual skills.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | IRCCS San Camillo, Venezia, Italy Academic / other |
| Locations | 2 sites (Padova, PD and 1 other locations) |
| Status | Recruiting |
| Started | April 1, 2023 |
| Main results expected | June 2025 |
| Study ends | June 2025 |
| Registry record updated | May 11, 2025 |
| Trial ID | NCT06965673 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals who have experienced a first unifocal ischemic or hemorrhagic stroke with specific visual and cognitive deficits.
✕Probably not a fit
Patients with a history of previous strokes or multifocal deficits may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the relationship between eye movements and visuospatial deficits in stroke patients, aiming to identify potential biomarkers through eye movement analysis during free viewing of natural scenes. It also explores the feasibility of a novel visual exploration training that utilizes auditory biofeedback to improve visuospatial skills. Participants will undergo neuropsychological assessments and neuroimaging to correlate eye movement characteristics with cognitive and functional outcomes. A subset of participants will receive the visual training alongside standard rehabilitation to assess its effectiveness compared to a control group.
Why it matters
Potential benefit: If successful, this approach could enhance rehabilitation strategies for stroke patients suffering from visuospatial deficits.
How similar studies have gone: While the approach of using eye movements as biomarkers is gaining interest, this specific combination of interventions is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Vigilant * First unifocal ischemic or hemorragic stroke * Presence of maximum two lacunae, clinically silent, smaller than 15 mm. in the structural MRI * Evident symptoms in the visual, attentive, memory, motor or language domain supported by the radiological exam Exclusion Criteria: * Previous stroke history, visible at the radiological exam * Multifocal deficit * Incapacity to remain vigilant during the required assessments * Claustrophobia and/or metallic objects which could prevent MRI acquisition * Presence of other neurological, psychiatric or medical conditions which may undermine interpretation of behavioral and neuroimaging results
Where it's running
-
Azienda Ospedaliera di Padova
Padova, Pd, Italy Recruiting -
IRCCS San Camillo
Venice-Lido, Ve, Italy Recruiting
Study contacts
- Principal investigator: Marco Zorzi — San Camillo IRCCS, Venice, Italy
- Study coordinator: Marco Zorzi
- Email: marco.zorzi@unipd.it
- Phone: +39 049 827 6618
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.