Evaluating exercise capacity and muscle function in children with pulmonary arterial hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess various physical and respiratory parameters in children diagnosed with pulmonary arterial hypertension (PAH) and compare them with healthy age- and sex-matched controls. Key evaluations will include pulmonary function, respiratory muscle strength, exercise capacity, muscle oxygenation, and arterial stiffness. The study will involve at least 13 children with PAH and 13 healthy controls, with all assessments conducted over two days using specialized devices and tests. The findings may help understand the impact of PAH on physical capabilities and overall health in children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients:

* Between the ages of 6-18
* Diagnosed with pulmonary arterial hypertension
* Stability of clinical condition and receiving standard medical treatment

Healthy controls:

* Between the ages of 6-18
* Willing to participate in the study

Exclusion Criteria:

Patients:

* Having any acute infection, orthopedic, neurological, cooperation, vision or hearing problems that may prevent during the measurements
* Participated in a planned exercise program in a last three months

Healthy controls:

* Having any acute or chronic illness
* Active or ex-smoker

Where it's running

• Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
  Ankara, Çankaya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Betül YOLERİ, Pt. MSc. — Gazi University
• Study coordinator: Meral BOŞNAK GÜÇLÜ, Prof. Dr.
• Email: meralbosnak@gazi.edu.tr
• Phone: +903122162647

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Sotatercept in Indian adults with pulmonary arterial hypertension on standard therapy

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• Once-daily treprostinil palmitil inhalation powder for PAH

  This study tests whether taking a daily inhaled treprostinil palmitil powder for 24 weeks improves exercise ability in adults with pulmonary arterial hypertension compared to a placebo.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.