Evaluating Etrasimod for Treating Ulcerative Colitis in Adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the safety, efficacy, and pharmacokinetics of etrasimod in adolescents aged 12 to under 18 years with moderately to severely active ulcerative colitis. Participants will undergo a 52-week treatment period, with the option to continue into a Long-Term Extension period lasting up to 4 years. The study will involve monitoring the effects of etrasimod on ulcerative colitis symptoms and overall health outcomes.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Have a diagnosis of ulcerative colitis (UC) that is moderately to severely active
* Participants are permitted to be receiving a therapeutic dose of select UC therapies

Exclusion criteria:

* Severe extensive colitis
* Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence or history of a fistula consistent with CD
* Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis

Where it's running

• Valley View Wellness Medical Center
  Garden Grove, California, United States Recruiting
• University of California San Francisco,
  San Francisco, California, United States Recruiting
• University of California San Francisco
  San Francisco, California, United States Recruiting
• University of California,San Francisco Pediatric ClinicalResearch Center (PCRC)
  San Francisco, California, United States Recruiting
• Arnold Palmer Hospital - Center for Digestive Health and Nutrition
  Orlando, Florida, United States Recruiting
• University of Chicago Medical Center
  Chicago, Illinois, United States Recruiting

Study contacts

• Study coordinator: Pfizer CT.gov Call Center
• Email: ClinicalTrials.gov_Inquiries@pfizer.com
• Phone: 1-800-718-1021

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.