Evaluating community health interventions for HIV prevention and treatment
SEARCH Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa Phase B
This study is testing a new approach to HIV prevention and treatment in communities in Kenya and Uganda to see if it can lower new HIV cases and improve overall health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80000 (estimated) |
| Ages | 15 Years and up |
| Sex | All |
| Sponsor | University of California, San Francisco Academic / other |
| Locations | 2 sites (Kisumu and 1 other locations) |
| Trial ID | NCT05768763 on ClinicalTrials.gov |
What this trial studies
This study assesses the impact of optimized prevention and treatment packages delivered through a precision community health model on HIV incidence and other health outcomes. It employs a community randomized trial design, focusing on dynamic prevention and treatment interventions based on previous findings and new advancements. The intervention includes community-enhanced outreach, person-centered care delivery, and data enhancements to improve intervention precision. Stakeholder consultations are integrated into the design to ensure collaboration with health authorities in Kenya and Uganda.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 15 years and older living in the SEARCH study communities.
Not a fit: Patients under 15 years of age or those living outside the SEARCH study communities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce HIV infections and improve overall health outcomes in the targeted communities.
How similar studies have performed: Other studies have shown success with community health interventions for HIV prevention, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \>= 15 years 2. Living in SEARCH study communities 3. Provided informed consent Exclusion Criteria: 1. \<15 years of age 2. Living outside SEARCH study communities 3. Unable to provide consent or parental co-consent as per country guidelines
Where this trial is running
Kisumu and 1 other locations
- SEARCH Office / GPRT — Kisumu, Kenya (Recruiting)
- Infectious Diseases Research Collaboration — Kampala, Uganda (Recruiting)
Study contacts
- Principal investigator: Diane Havlir, MD — University of California, San Francisco
- Study coordinator: Tamara Clark, MHS
- Email: tamara.clark@ucsf.edu
- Phone: 628-206-8790
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.