Evaluating blood purification therapies in critically ill patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry aims to assess the effectiveness of extracorporeal blood purification therapies (EBPT) in critically ill patients suffering from acute kidney injury and/or multiorgan failure. The study will analyze whether specific subpopulations of patients benefit more from these therapies, particularly focusing on their hemodynamic stability and multiorgan dysfunction scores. By identifying these clusters, the research seeks to enhance the personalized application of EBPT in critical care settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* critically ill patients in the ICU
* one of this EPB therapy:
* CRRT/IHD/Hybrid therapies for support//replacement renal function
* immunomodulation achieved by "high cut-off membranes", "endotoxins and/or cytokines adsorbent membranes" or by high-volume hemofiltration

Exclusion Criteria:

* patients treated only by Cytosorb® and/or Toraymyxin® therapies

Where it's running

• Ospedale S. Giuseppe
  Empoli, Firenze, Italy Recruiting
• Ospedale Versilia
  Lido di Camaiore, Lucca, Italy Recruiting
• Humanitas Research Hospital
  Rozzano, Milano, Italy Recruiting
• IRCCS Policlinico S. Donato
  San Donato Milanese, Milano, Italy Recruiting
• Ospedale S. Gerardo
  Monza, Monza-Brianza, Italy Recruiting
• Ospedale A. Perrino
  Brindisi, Italy Recruiting

Study contacts

• Principal investigator: Gianluca Villa, MD — University of Florence, Florence, Italy
• Study coordinator: Gianluca Villa, MD
• Email: gianluca.villa@unifi.it
• Phone: +393207615547

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Understanding how patients tolerate fluid removal during kidney support in the ICU

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• Sodium bicarbonate for critically ill patients with metabolic acidosis and AKI

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.