Evaluating blood flow in acute ischemic stroke using advanced imaging techniques
Application of a Noninvasive Quantitative Assessment System for Cerebral Perfusion Function in the "Green Channel" of Acute Stroke
This study is testing a new imaging technique to see if it can better measure blood flow in the brains of people who have had an acute ischemic stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT05213793 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effectiveness of multi-delay arterial spin labeling (ASL) in assessing cerebral blood flow in patients with acute ischemic stroke. A total of 200 patients will be enrolled and undergo various imaging techniques, including CTP and multi-delay ASL, to evaluate perfusion levels and the extent of reversible ischemic injury. The study aims to compare the accuracy and quality of these imaging methods in diagnosing stroke and predicting clinical outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals who have experienced an ischemic stroke within the last 24 hours and have anterior circulation occlusion confirmed by imaging.
Not a fit: Patients who are pregnant or have contraindications to MRI scans will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of stroke diagnosis and improve patient management strategies.
How similar studies have performed: Previous studies have shown promising results with advanced imaging techniques in stroke diagnosis, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Ischemic stroke within 24h； 2. Anterior circulation occlusion confirmed by conventional angiography or magnetic resonance angiography； Exclusion Criteria: 1. Pregnancy and other contraindication to MRI scan； 2. Informed consent not obtained.
Where this trial is running
Beijing, Beijing
- Xuanwu Hospital — Beijing, Beijing, China (Recruiting)
Study contacts
- Study coordinator: qingfeng Ma, MD
- Email: m.qingfeng@163.com
- Phone: +8613601069493
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.