Evaluating biomarkers and EEG in pre-eclampsia and eclampsia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the discriminative power of the Bispectral Index (BIS), the soluble FMS-like Tyrosine Kinase to Placental Growth Factor (sFIT:PIGF) ratio, and adrenomedullin as mortality risk stratifiers in patients with eclampsia or pre-eclampsia. By analyzing these biomarkers and EEG data, the study seeks to classify the severity and progression of pre-eclampsia, which is a significant cause of maternal morbidity and mortality. The study will involve 24 patients and will utilize a standardized risk assessment model known as PIERS to correlate clinical findings with the degree of pre-eclampsia.

Why it matters

Who can join: the full rules

Inclusion Criteria

1. Pregnancy at any stage (3 trimesters)
2. Eclampsia (Frank eclampsia) will be the crux of the study
3. Pre-eclampsia that is suspected will end up with Frank Eclampsia

Exclusion criteria:

1. Any neurological conditions that can alter the electroencephalography like epilepsy
2. Any medical conditions that can alter the electroencephalography like hypoglycemia

Where it's running

• Medical Ethics Committee, University Malaya Medical Centre
  Kuala Lumpur, Malaysia Recruiting

Study contacts

• Principal investigator: Ashraf Dahaba, MD — Guest Professor
• Study coordinator: Ashraf Dahaba, MD
• Email: ashraf.dahaba@medunigraz.at
• Phone: 00436509006761

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Preeclampsia Biomarker Test in African Women

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• Kidney and heart prevention program after preeclampsia

  This program will see if follow-up care plus a biobank can help identify and manage long-term kidney and heart risks for women who had preeclampsia, HELLP, eclampsia, or pregnancy-related kidney disease.

  Recruiting University Hospital Schleswig-Holstein · Kiel · NCT07151339

• Registry for women with preeclampsia and related conditions

  This study is collecting health information from women with preeclampsia and related conditions to help researchers learn more about the causes and find better treatments for this serious pregnancy issue.

  Recruiting Preeclampsia Foundation · Melbourne, Florida · NCT06377878

• Using low-dose aspirin after preeclampsia to improve recovery

  This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.

  Recruiting Phase 4 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06281665

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.