Evaluating Aortic Valve Composition in Aortic Stenosis
Role of Aortic Valve Composition in Pathophysiology and Diagnosis of Aortic Stenosis
Medical University of Warsaw · NCT06136689
This study looks at how the makeup of aortic valves changes in people with aortic stenosis to better understand the condition and improve diagnosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 55 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Medical University of Warsaw (other) |
| Locations | 2 sites (Katowice and 1 other locations) |
| Trial ID | NCT06136689 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the differences in aortic valve composition across various stages and phenotypes of aortic stenosis. Utilizing non-invasive imaging techniques and histological analysis, the research aims to enhance understanding of the pathophysiology and diagnostic processes related to aortic valve disease. Participants will undergo pre-surgical computed tomography angiography as part of their standard care, with informed consent obtained prior to participation.
Who should consider this trial
Good fit: Ideal candidates include individuals scheduled for aortic valve replacement or heart transplant as determined by their local Heart Team.
Not a fit: Patients who are not undergoing surgical intervention for aortic valve issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods and treatment strategies for patients with aortic stenosis.
How similar studies have performed: While this approach is innovative, similar studies have not been widely reported, indicating a potential novel exploration in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aortic valve replacement or heart transplant as part of standard care decided by the local Heart Team * pre-surgical computed tomography angiography * informed consent
Where this trial is running
Katowice and 1 other locations
- Medical University of Silesia — Katowice, Poland (RECRUITING)
- Poznan University of Medical Sciences — Poznań, Poland (RECRUITING)
Study contacts
- Study coordinator: Kajetan Grodecki, MD, PhD
- Email: kajetan.grodecki@gmail.com
- Phone: 0048 660675782
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aortic Stenosis, Aortic Valve Disease, Aortic Valve Calcification