Evaluating airflow limitation in COPD, emphysema, and asthma overlap

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the site and mechanisms of expiratory airflow limitation in chronic smokers with COPD, emphysema, and asthma-COPD overlap. It involves detailed lung function testing, including spirometry and high-resolution CT scans, to identify whether airflow limitation is due to large central airways or small peripheral airways. The study also examines the relationship between airflow limitation and lung elastic recoil, as well as the extent of emphysema. Blood tests will be conducted to gather additional health information relevant to the conditions being studied.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* asthma- copd overlap
* emphysema in smokers with smoking history \> 15 pack years
* COPD/ bronchitis and bronchiectasis in smokers with smoking history
* \>15 pack years

Exclusion Criteria:other pulmonary or systemic diagnosis

* non smokers
* any other pulmonary diagnosis
* pulmonary fibrosis

Where it's running

• Arthur F Gelb MD
  Lakewood, California, United States Recruiting
• Arthur F Gelb MD
  Lakewood, California, United States Recruiting

Study contacts

• Principal investigator: Arthur F Gelb, MD — Clin Prof Geffen School of Medicine at UCLA Medical Center
• Study coordinator: Arthur F Gelb, MD
• Email: afgelb@msn.com
• Phone: 562-633-2204

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.