Evaluating a specific surgical technique for epilepsy treatment

Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach

Observational University Hospital, Montpellier · NCT06915649

This study is trying to see how well a specific surgical technique for epilepsy works in helping patients control their seizures and what factors might improve their recovery.

Quick facts

Study typeObservational
Enrollment3504 (estimated)
SexAll
SponsorUniversity Hospital, Montpellier Academic / other
Locations1 site (Montpellier, Hérault)
Trial IDNCT06915649 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the long-term clinical outcomes and complications of amygdalo-hippocampectomy performed using a technique developed by Professor Coubes. It will analyze data from 234 patients treated over the past 30 years at the CHU de Montpellier, focusing on seizure outcomes, post-operative complications, and factors influencing recovery. The study seeks to identify variables associated with improved seizure control following surgery for conditions like hippocampal sclerosis and other temporal lobe diseases.

Who should consider this trial

Good fit: Ideal candidates are patients who have undergone amygdalo-hippocampectomy using the specified surgical technique.

Not a fit: Patients who have not had the exact amygdalo-hippocampectomy procedure will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance surgical approaches for epilepsy treatment, leading to better seizure control and improved quality of life for patients.

How similar studies have performed: Other studies have shown varying success with similar surgical techniques, but this specific evaluation of Professor Coubes' method is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who had undergone an Amygdalo-Hippocampectomy according to the surgical procedure that we describe

Exclusion Criteria:

* Patients who did not have this exact procedure.

Where this trial is running

Montpellier, Hérault

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hippocampal SclerosisDysembryoplastic Neuroepithelial TumorCortical DysplasiaGangliogliomaCavernomaEpidermal CystHamartomaPilocytic Astrocytoma
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.