Evaluating a new stent graft for treating acute aortic syndrome
Official title: Real-world Experience With the Castor Single Branch Stent Graft in the Management of Acute Aortic Syndrome
Run by First Affiliated Hospital Xi'an Jiaotong University · NCT05965453 · Data updated 2026-11-12
This study is testing a new type of stent graft to see if it is safe and effective for people with acute aortic syndrome who don't have enough support for traditional treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 95 Years |
| Sex | All |
| Enrollment | 205 (estimated) |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Status | Recruiting |
| Started | June 1, 2018 |
| Main results expected | June 1, 2032 |
| Study ends | June 1, 2032 |
| Registry record updated | July 28, 2023 |
| Trial ID | NCT05965453 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with acute Stanford type B aortic syndrome and an inadequate proximal landing zone who received the Castor stent graft between June 2018 and June 2022.
✕Probably not a fit
Patients with an adequate proximal landing zone or those who have previously undergone endovascular repair of the aorta will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the safety and effectiveness of the Castor single branch stent graft in patients with acute aortic syndrome who have an inadequate proximal landing zone. A total of 205 patients who underwent thoracic endovascular aortic repair using this stent graft from June 2018 to June 2022 will be followed up for up to 10 years. The study will involve routine assessments, including physical examinations, laboratory tests, and CT angiography at various intervals post-procedure to monitor outcomes.
Why it matters
Potential benefit: If successful, this study could provide a safer and more effective treatment option for patients with acute aortic syndrome who have limited surgical options.
How similar studies have gone: While similar studies have explored endovascular treatments for aortic conditions, the specific use of the Castor single branch stent graft in this context is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute Stanford type B aortic syndrome who received thoracic endovascular aortic repair by meant of Castor single branch stent graft from June 2018 to June 2022 Exclusion Criteria: * Patients with acute type B aortic syndrome with an adequate proximal landing zone (≥15mm) * Previous endovascular repair of the aorta * Patients with missing data and loss of follow-up
Where it's running
-
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China Recruiting
Study contacts
- Study coordinator: Hongyan Tian, MD
- Email: tianhongyan2020@163.com
- Phone: 0086-13891981101
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using ADD-RS and D-dimer to rule out acute aortic syndrome in the ED
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Using statins to protect heart health after aortic surgery
This study tests if the cholesterol-lowering drug rosuvastatin can help people recover better and protect their heart health after surgery for serious aortic problems.
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Adding anti-inflammatory treatment for acute aortic conditions
This registry will follow adults having surgery for acute aortic syndrome to see if inflammation and anti-inflammatory approaches affect recovery and complications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.