Evaluating a new packaging design for opioid medications

The Feasibility and Effectiveness of an Opioid Package Prototype (OPP) to Impact Opioid Prescribing, Dispensing, and Patient Use Outcomes

Not applicable Interventional UConn Health · NCT04598074

This study is testing a new packaging design for oxycodone to see if it helps patients after orthopedic surgery use their pain medication more safely and effectively compared to regular bottles.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment352 (estimated)
Ages18 Years and up
SexAll
SponsorUConn Health Academic / other
Locations1 site (Farmington, Connecticut)
Trial IDNCT04598074 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to assess the impact of the Opioid Package Prototype (OPP) on the prescribing, dispensing, and patient use of oxycodone among patients undergoing orthopedic surgery. The study will compare the effectiveness of the OPP against standard amber vials in managing post-operative pain. It will also evaluate the feasibility of the new packaging for prescribers, pharmacists, and patients. Data collected will help optimize packaging and labeling to improve medication safety and usage.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are undergoing orthopedic surgery and require oxycodone for post-operative pain management.

Not a fit: Patients not undergoing orthopedic surgery or those who do not require opioid medication will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to safer and more effective opioid prescribing practices, reducing the risk of misuse.

How similar studies have performed: While there have been studies on opioid packaging, this specific approach with the OPP is relatively novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The patient is 18 years and older;
2. The patient is one of the participating surgeons;
3. The patient is receiving orthopaedic surgery that involves the use of opioid medication for post-operative pain;
4. The patient is willing to receive oxycodone medication;
5. The patient is willing and able to receive medication at the UConn Health Specialty Pharmacy, located in the Exchange across the street from the main entrance of UConn Health;
6. The patient is willing and able to use a MyChart account;
7. The patient is able to read and understand English; and
8. The patient is able to understand the study procedures and their involvement in the study.

Exclusion Criteria:

-

Where this trial is running

Farmington, Connecticut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid UseOpioid Prescribing, Dispensing, and Patient Useoxycodoneopioidopioidspackagepackagingpost-surgical pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.