Evaluating a new method for identifying pathogens and antibiotic resistance in sepsis patients
Official title: Evaluation of the Performance of the IDBIORIV Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis
Run by Hospices Civils de Lyon · NCT06219135 · Data updated 2026-11-12
This study is testing a new method to quickly identify germs and their resistance to antibiotics in sepsis patients to see if it can improve their treatment and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Day and up |
| Sex | All |
| Enrollment | 1372 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 23 sites (Bron and 22 other locations) |
| Status | Recruiting |
| Started | March 21, 2024 |
| Main results expected | November 21, 2026 |
| Study ends | November 21, 2026 |
| Registry record updated | June 10, 2026 |
| Trial ID | NCT06219135 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are hospitalized patients of any age showing signs of infection with a confirmed positive blood culture.
✕Probably not a fit
Patients under court protection or guardianship may not benefit from this study due to eligibility restrictions.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the IDBIORIV method for identifying pathogens and testing antibiotic susceptibility in patients diagnosed with sepsis. Sepsis is a critical condition resulting from bloodstream infections, and timely identification of the causative microorganisms is crucial for effective treatment. The study aims to assess the performance of this method compared to standard techniques used in clinical microbiology laboratories. By improving the speed and accuracy of pathogen identification, the study seeks to enhance patient outcomes and reduce mortality associated with sepsis.
Why it matters
Potential benefit: If successful, this method could significantly improve the speed of diagnosis and treatment for sepsis patients, potentially increasing survival rates.
How similar studies have gone: While the study employs established techniques, the specific application of the IDBIORIV method in this context is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult or child patient * Hospitalized in one of the departments registered with Hospices Civils de Lyon * Showing signs of infection * Confirmed by a 1st positive blood culture * Patient or close relative (trustworthy person or family member) or holder of parental authority who has given his or her non-objection after receiving the information note Exclusion Criteria: * Patients under court protection * Patients under guardianship or curatorship
Where it's running
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Femme Mère enfant Hospital
Bron, France Recruiting -
Femme Mère Enfant Hospital
Bron, France Recruiting -
Louis Pradel Hospital
Bron, France Recruiting -
Louis Pradel Hospital
Bron, France Recruiting -
Louis Pradel Hospital
Bron, France Recruiting -
Pierre Wertheimer Hospital
Bron, France Recruiting
Show 17 more locations
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Edouard Herriot Hospital
Lyon, France Recruiting -
Edouard Herriot Hospital
Lyon, France Recruiting -
Croix Rousse Hospital
Lyon, France Recruiting -
Croix Rousse Hospital
Lyon, France Recruiting -
Croix Rousse Hospital
Lyon, France Recruiting -
Croix Rousse Hospital
Lyon, France Recruiting -
Croix Rousse Hospital
Lyon, France Recruiting -
Lyon Sud Hospital
Pierre-Bénite, France Recruiting -
Lyon Sud Hospital
Pierre-Bénite, France Recruiting -
Charpennes Hospital
Villeurbanne, France Recruiting -
Femme Mère enfant Hospital
Bron, France Not yet recruiting -
Edouard Herriot Hospital
Lyon, France Not yet recruiting -
Edouard Herriot Hospital
Lyon, France Not yet recruiting -
Croix Rousse Hospital
Lyon, France Not yet recruiting -
Croix Rousse Hospital
Lyon, France Not yet recruiting -
Lyon Sud Hospital
Pierre-Bénite, France Not yet recruiting -
Lyon Sud Hospital
Pierre-Bénite, France Not yet recruiting
Study contacts
- Study coordinator: François VANDENESCH, Pr
- Email: francois.vandenesch@univ-lyon1.fr
- Phone: 4 72 07 11 11
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Ruta C and Vitamin C in Sepsis: Adding antioxidants to standard care
This trial tests whether adding Ruta C (rutin plus vitamin C) or vitamin C alone to standard sepsis treatment helps adults in the ICU stay shorter and recover better.
-
Early detection of sepsis-related blood clotting problems in severe burn patients
This study tests how well the JAAM-2 score can detect sepsis-induced coagulopathy early in adults with severe burns who develop sepsis in the ICU.
-
Neutrophil EMR3 as a biomarker for sepsis in ICU patients
Researchers will test whether measuring EMR3 on neutrophils helps diagnose sepsis, monitor progression, and predict outcomes in adults in Chinese ICUs.
-
Thymalfasin added to standard care for adults with sepsis and immune dysfunction
This study tests whether thymosin alpha-1 helps restore immune function in adults with sepsis who have weakened immunity.
-
Multicenter group study of sepsis and ARDS in China
This study tests how sepsis and ARDS differ among adults across several Chinese hospitals and builds a biobank to understand why some patients do better or worse.
-
Non-invasive hemodynamic guidance for sepsis care on medical wards
This trial tests whether guiding fluid and vasopressor therapy for sepsis using non-invasive hemodynamic measurements works better than standard care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.