EUS-guided celiac plexus block for chronic pancreatitis pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial evaluates the effectiveness of endoscopic ultrasonography-guided celiac plexus block (EUS-CPB) in reducing abdominal pain for patients suffering from chronic pancreatitis. The procedure involves injecting a combination of a steroid and a local anesthetic into the celiac plexus to alleviate pain, which is a significant complication of the disease. Participants will be compared against a sham procedure to assess the true efficacy of EUS-CPB. The study aims to provide insights into pain management strategies for chronic pancreatitis patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Abdominal pain of at least 3 months duration and a VAS score ≥ 3, with or without the use of narcotic analgesics.
* Diagnosis of chronic pancreatitis on EUS examination, with ≥ 5 features on EUS.
* No other cause of abdominal pain

Exclusion Criteria:

* Age \< 18 years.
* History of prior EUS-CPB.
* Use of anticoagulants that cannot be discontinued for the procedure.
* Clinically significant allergy to bupivacaine or triamcinolone.
* Unable to obtain consent for the procedure from either the patient or LAR.
* Intrauterine pregnancy.

Where it's running

• Orlando Health
  Orlando, Florida, United States Recruiting

Study contacts

• Study coordinator: Charles Melbern Wilcox, MD
• Email: Charles.Wilcox@orlandohealth.com
• Phone: 321-841-2431

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.